Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXX11_RS10460 Genome accession   NZ_CP025851
Coordinates   2065597..2066229 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 510016     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2060597..2071229
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX11_RS10435 yheS 2060766..2062679 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CXX11_RS10440 yheT 2062679..2063701 (+) 1023 WP_000057379.1 hydrolase -
  CXX11_RS10445 yheU 2063695..2063913 (+) 219 WP_000907085.1 YheU family protein -
  CXX11_RS10450 prkB 2063967..2064836 (+) 870 WP_001274680.1 phosphoribulokinase -
  CXX11_RS10455 yhfA 2064891..2065295 (-) 405 WP_001148910.1 OsmC family protein -
  CXX11_RS10460 crp 2065597..2066229 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXX11_RS10465 yhfK 2066280..2068370 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CXX11_RS10470 argD 2068437..2069657 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXX11_RS10475 pabA 2069743..2070306 (-) 564 WP_001401214.1 aminodeoxychorismate synthase component 2 -
  CXX11_RS10480 fic 2070338..2070940 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CXX11_RS10485 yhfG 2070930..2071097 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220264 CXX11_RS10460 WP_000242755.1 2065597..2066229(+) (crp) [Escherichia coli strain 510016]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220264 CXX11_RS10460 WP_000242755.1 2065597..2066229(+) (crp) [Escherichia coli strain 510016]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467