Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXX14_RS08755 Genome accession   NZ_CP025849
Coordinates   1870275..1870907 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 600468     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1865275..1875907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX14_RS08730 yhfG 1865407..1865574 (+) 168 WP_000736860.1 YhfG family protein -
  CXX14_RS08735 fic 1865564..1866166 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXX14_RS08740 pabA 1866198..1866761 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CXX14_RS08745 argD 1866847..1868067 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXX14_RS08750 yhfK 1868134..1870224 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  CXX14_RS08755 crp 1870275..1870907 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXX14_RS08760 yhfA 1871209..1871613 (+) 405 WP_001148908.1 OsmC family protein -
  CXX14_RS08765 prkB 1871668..1872537 (-) 870 WP_001274684.1 phosphoribulokinase -
  CXX14_RS08770 yheU 1872591..1872809 (-) 219 WP_000907085.1 YheU family protein -
  CXX14_RS08775 yheT 1872803..1873825 (-) 1023 WP_000057405.1 hydrolase -
  CXX14_RS08780 yheS 1873825..1875738 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220187 CXX14_RS08755 WP_000242755.1 1870275..1870907(-) (crp) [Escherichia coli strain 600468]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220187 CXX14_RS08755 WP_000242755.1 1870275..1870907(-) (crp) [Escherichia coli strain 600468]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment