Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BVZ63_RS05215 Genome accession   NZ_CP020014
Coordinates   1043300..1043974 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain 11P6H     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1038300..1048974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BVZ63_RS05180 (BVZ63_1055) rpmG 1039217..1039387 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  BVZ63_RS05185 (BVZ63_1056) rpmB 1039399..1039635 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  BVZ63_RS05190 (BVZ63_1057) radC 1039848..1040513 (-) 666 WP_041174703.1 RadC family protein -
  BVZ63_RS05195 (BVZ63_1058) coaBC 1040677..1041879 (+) 1203 WP_105197740.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  BVZ63_RS05200 (BVZ63_1059) dut 1041927..1042382 (+) 456 WP_005631431.1 dUTP diphosphatase -
  BVZ63_RS05205 (BVZ63_1060) slmA 1042386..1043042 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  BVZ63_RS05210 (BVZ63_1061) - 1043064..1043315 (+) 252 WP_005647999.1 YheU family protein -
  BVZ63_RS05215 (BVZ63_1062) crp 1043300..1043974 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  BVZ63_RS05220 (BVZ63_1063) rlmC 1044339..1045517 (-) 1179 WP_005686221.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  BVZ63_RS05225 (BVZ63_1064) nagZ 1045514..1046566 (-) 1053 WP_005686223.1 beta-N-acetylhexosaminidase -
  BVZ63_RS05230 (BVZ63_1065) - 1046570..1046920 (-) 351 WP_005686225.1 YcfL family protein -
  BVZ63_RS05235 (BVZ63_1066) - 1046920..1047270 (-) 351 WP_005686227.1 HIT domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=220064 BVZ63_RS05215 WP_005647998.1 1043300..1043974(+) (crp) [Haemophilus influenzae strain 11P6H]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=220064 BVZ63_RS05215 WP_005647998.1 1043300..1043974(+) (crp) [Haemophilus influenzae strain 11P6H]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTACGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment