Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXX37_RS17520 Genome accession   NZ_CP025842
Coordinates   3502953..3503585 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 720632     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3497953..3508585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX37_RS17495 yhfG 3498085..3498252 (+) 168 WP_000736860.1 YhfG family protein -
  CXX37_RS17500 fic 3498242..3498844 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXX37_RS17505 pabA 3498876..3499439 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CXX37_RS17510 argD 3499525..3500745 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXX37_RS17515 yhfK 3500812..3502902 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CXX37_RS17520 crp 3502953..3503585 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXX37_RS17525 yhfA 3503887..3504291 (+) 405 WP_001148910.1 OsmC family protein -
  CXX37_RS17530 prkB 3504346..3505215 (-) 870 WP_001274680.1 phosphoribulokinase -
  CXX37_RS17535 yheU 3505269..3505487 (-) 219 WP_000907085.1 YheU family protein -
  CXX37_RS17540 yheT 3505481..3506503 (-) 1023 WP_000057379.1 hydrolase -
  CXX37_RS17545 yheS 3506503..3508416 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220044 CXX37_RS17520 WP_000242755.1 3502953..3503585(-) (crp) [Escherichia coli strain 720632]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220044 CXX37_RS17520 WP_000242755.1 3502953..3503585(-) (crp) [Escherichia coli strain 720632]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment