Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BV139_RS05770 Genome accession   NZ_CP020012
Coordinates   1131314..1131988 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain 6P24H2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1126314..1136988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV139_RS05735 (BV139_1162) rpmG 1127230..1127400 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  BV139_RS05740 (BV139_1163) rpmB 1127412..1127648 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  BV139_RS05745 (BV139_1164) radC 1127862..1128527 (-) 666 WP_032821549.1 RadC family protein -
  BV139_RS05750 (BV139_1165) coaBC 1128691..1129893 (+) 1203 WP_005686217.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  BV139_RS05755 (BV139_1166) dut 1129941..1130396 (+) 456 WP_005631431.1 dUTP diphosphatase -
  BV139_RS05760 (BV139_1167) slmA 1130400..1131056 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  BV139_RS05765 (BV139_1168) - 1131078..1131329 (+) 252 WP_005647999.1 YheU family protein -
  BV139_RS05770 (BV139_1169) crp 1131314..1131988 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  BV139_RS05775 (BV139_1170) rlmC 1132353..1133531 (-) 1179 WP_005686221.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  BV139_RS05780 (BV139_1171) nagZ 1133528..1134580 (-) 1053 WP_005686223.1 beta-N-acetylhexosaminidase -
  BV139_RS05785 (BV139_1172) - 1134584..1134934 (-) 351 WP_005686225.1 YcfL family protein -
  BV139_RS05790 (BV139_1173) - 1134934..1135284 (-) 351 WP_005686227.1 HIT domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=219992 BV139_RS05770 WP_005647998.1 1131314..1131988(+) (crp) [Haemophilus influenzae strain 6P24H2]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=219992 BV139_RS05770 WP_005647998.1 1131314..1131988(+) (crp) [Haemophilus influenzae strain 6P24H2]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTACGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment