Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BV134_RS05245 Genome accession   NZ_CP020011
Coordinates   1037187..1037861 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain 67P56H1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1032187..1042861
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV134_RS05210 (BV134_1055) rpmG 1033101..1033271 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  BV134_RS05215 (BV134_1056) rpmB 1033283..1033519 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  BV134_RS05220 (BV134_1057) radC 1033733..1034398 (-) 666 WP_013527272.1 RadC family protein -
  BV134_RS05225 (BV134_1058) coaBC 1034561..1035763 (+) 1203 WP_050822922.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  BV134_RS05230 (BV134_1059) dut 1035811..1036266 (+) 456 WP_014550997.1 dUTP diphosphatase -
  BV134_RS05235 (BV134_1060) slmA 1036270..1036929 (+) 660 WP_014550996.1 nucleoid occlusion factor SlmA -
  BV134_RS05240 (BV134_1061) - 1036951..1037202 (+) 252 WP_005647999.1 YheU family protein -
  BV134_RS05245 (BV134_1062) crp 1037187..1037861 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  BV134_RS05250 (BV134_1063) rlmC 1038226..1039401 (-) 1176 WP_014550995.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  BV134_RS05255 (BV134_1064) nagZ 1039394..1040449 (-) 1056 WP_042601923.1 beta-N-acetylhexosaminidase -
  BV134_RS05260 (BV134_1065) - 1040453..1040803 (-) 351 WP_014550994.1 YcfL family protein -
  BV134_RS05265 (BV134_1066) hinT 1040803..1041153 (-) 351 WP_005627389.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=219955 BV134_RS05245 WP_005647998.1 1037187..1037861(+) (crp) [Haemophilus influenzae strain 67P56H1]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=219955 BV134_RS05245 WP_005647998.1 1037187..1037861(+) (crp) [Haemophilus influenzae strain 67P56H1]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTTACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment