Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BV134_RS02895 Genome accession   NZ_CP020011
Coordinates   580199..581419 (+) Length   406 a.a.
NCBI ID   WP_042601844.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 67P56H1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 575199..586419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV134_RS02875 (BV134_587) corC 576162..577061 (-) 900 WP_011961742.1 CNNM family magnesium/cobalt transport protein CorC -
  BV134_RS02880 (BV134_589) ampD 577684..578244 (-) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  BV134_RS02885 pilA 578359..578808 (+) 450 WP_042601842.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  BV134_RS02890 (BV134_591) pilB 578805..580202 (+) 1398 WP_042601843.1 GspE/PulE family protein Machinery gene
  BV134_RS02895 (BV134_592) pilC 580199..581419 (+) 1221 WP_042601844.1 type II secretion system F family protein Machinery gene
  BV134_RS02900 (BV134_593) pilD 581416..582108 (+) 693 WP_050822711.1 prepilin peptidase Machinery gene
  BV134_RS02905 (BV134_594) rho 582162..583424 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  BV134_RS02910 (BV134_595) metJ 583672..583989 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  BV134_RS02915 (BV134_596) cueR 584003..584389 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  BV134_RS02920 (BV134_597) - 584466..584672 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  BV134_RS02925 (BV134_598) - 584746..584952 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  BV134_RS02930 (BV134_599) - 585038..585244 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  BV134_RS02935 (BV134_600) - 585330..585536 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46205.41 Da        Isoelectric Point: 9.7152

>NTDB_id=219942 BV134_RS02895 WP_042601844.1 580199..581419(+) (pilC) [Haemophilus influenzae strain 67P56H1]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQDCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=219942 BV134_RS02895 WP_042601844.1 580199..581419(+) (pilC) [Haemophilus influenzae strain 67P56H1]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAGATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.98
  pilC Haemophilus influenzae Rd KW20

97.291

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment