Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXX41_RS10710 Genome accession   NZ_CP025840
Coordinates   2196475..2197107 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 214-4     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2191475..2202107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX41_RS10685 yhfG 2191607..2191774 (+) 168 WP_000736860.1 YhfG family protein -
  CXX41_RS10690 fic 2191764..2192366 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXX41_RS10695 pabA 2192398..2192961 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CXX41_RS10700 argD 2193047..2194267 (+) 1221 WP_000963768.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXX41_RS10705 yhfK 2194334..2196424 (-) 2091 WP_001353634.1 YccS/YhfK family putative transporter -
  CXX41_RS10710 crp 2196475..2197107 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXX41_RS10715 yhfA 2197409..2197813 (+) 405 WP_001148910.1 OsmC family protein -
  CXX41_RS10720 prkB 2197868..2198737 (-) 870 WP_001274680.1 phosphoribulokinase -
  CXX41_RS10725 yheU 2198791..2199009 (-) 219 WP_000907085.1 YheU family protein -
  CXX41_RS10730 yheT 2199003..2200025 (-) 1023 WP_000057379.1 hydrolase -
  CXX41_RS10735 yheS 2200025..2201938 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=219942 CXX41_RS10710 WP_000242755.1 2196475..2197107(-) (crp) [Escherichia coli strain 214-4]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=219942 CXX41_RS10710 WP_000242755.1 2196475..2197107(-) (crp) [Escherichia coli strain 214-4]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment