Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   SPYM18_RS01355 Genome accession   NC_003485
Coordinates   255022..256092 (+) Length   356 a.a.
NCBI ID   WP_011017335.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS8232     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 250022..261092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM18_RS01340 (spyM18_0281) amiA 250550..252520 (+) 1971 WP_011017333.1 peptide ABC transporter substrate-binding protein Regulator
  SPYM18_RS01345 (spyM18_0282) amiC 252585..254087 (+) 1503 WP_011017334.1 ABC transporter permease Regulator
  SPYM18_RS01350 (spyM18_0283) amiD 254087..255013 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  SPYM18_RS01355 (spyM18_0284) amiE 255022..256092 (+) 1071 WP_011017335.1 ABC transporter ATP-binding protein Regulator
  SPYM18_RS01360 (spyM18_0285) amiF 256085..257008 (+) 924 WP_011017336.1 ATP-binding cassette domain-containing protein Regulator
  SPYM18_RS10735 - 257046..257129 (-) 84 Protein_227 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39763.87 Da        Isoelectric Point: 5.6707

>NTDB_id=21921 SPYM18_RS01355 WP_011017335.1 255022..256092(+) (amiE) [Streptococcus pyogenes MGAS8232]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLEFNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=21921 SPYM18_RS01355 WP_011017335.1 255022..256092(+) (amiE) [Streptococcus pyogenes MGAS8232]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTTTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATTGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)

ABC transporter (ABC_tran)

(29-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment