Detailed information NTG0021922

Bioinformatically predicted

Overview

• Name: amiF
• Type: Regulator
• Locus tag: SPYM18_RS01360
• Genome accession: NC_003485
• Coordinates: 256085..257008 (+)
• Length: 307 a.a.
• NCBI ID: WP_011017336.1
• Uniprot ID: Q8P2L5
• Organism: Streptococcus pyogenes MGAS8232
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 251085..262008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYM18_RS01345 (spyM18_0282)	amiC	252585..254087 (+)	1503	WP_011017334.1	ABC transporter permease	Regulator
SPYM18_RS01350 (spyM18_0283)	amiD	254087..255013 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
SPYM18_RS01355 (spyM18_0284)	amiE	255022..256092 (+)	1071	WP_011017335.1	ABC transporter ATP-binding protein	Regulator
SPYM18_RS01360 (spyM18_0285)	amiF	256085..257008 (+)	924	WP_011017336.1	ATP-binding cassette domain-containing protein	Regulator
SPYM18_RS10735	-	257046..257129 (-)	84	Protein_227	IS3 family transposase	-

Sequence

Protein

• Length: 307 a.a.
• Molecular weight: 34773.94 Da
• Isoelectric Point: 6.3176

>NTDB_id=21922 SPYM18_RS01360 WP_011017336.1 256085..257008(+) (amiF) [Streptococcus pyogenes MGAS8232]
MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGESGSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKS
EANELIRKIQMIFQDPAASLNERATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKDLTYLFIAHDLSVVRFISDRIAVIHKGVIVEVAETEELFN
NPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHDYTLDKPSMVEIKPNHFVWANQAEIEKYQKEL

Nucleotide

• Length: 924 bp

>NTDB_id=21922 SPYM18_RS01360 WP_011017336.1 256085..257008(+) (amiF) [Streptococcus pyogenes MGAS8232]
ATGTCTGAGAAATTAGTCGAAGTAAAAGACCTAGAAATTTCCTTCGGAGAAGGAAAGAAAAAATTTGTTGCAGTTAAAAA
TGCTAATTTCTTTATTAAAAAAGGAGAAACCTTTTCTTTAGTTGGAGAATCTGGGAGTGGTAAAACAACAATTGGTCGTG
CTATTATTGGTTTGAACGATACTAGTTCAGGTCAAATTTTATACGATGGGAAAGTAATTAATGGCAGAAAATCAAAATCA
GAAGCCAATGAGCTCATTCGTAAAATTCAAATGATTTTCCAAGATCCCGCTGCTAGTTTGAATGAACGAGCAACCGTTGA
CTACATCATTTCAGAAGGTCTTTATAACTTTAATCTGTTTAAAACAGAGGAAGAACGTAAAGAAAAAATTAAGAACATGA
TGGCCGAAGTTGGTTTGCTATCAGAGCATTTGACGCGCTACCCACATGAATTTTCAGGAGGTCAACGTCAGCGGATCGGT
ATCGCTAGAGCCCTAGTAATGAACCCTGAATTCGTTATTGCTGATGAACCGATTTCAGCTTTGGACGTTTCCGTTCGCGC
ACAGGTTTTAAACCTTCTCAAACGGATGCAAGCCGAAAAAGATTTGACTTATCTCTTCATTGCCCATGATCTTTCAGTCG
TTCGCTTTATTTCAGATCGTATTGCGGTTATCCATAAAGGGGTTATTGTAGAAGTTGCAGAAACAGAAGAACTGTTTAAT
AACCCAATTCATCCCTACACCCAATCTTTGTTATCAGCCGTGCCTATCCCAGATCCAATTTTAGAGCGTCAAAAAGAACT
TGTTGTCTATCATCCAGACCAGCATGATTATACATTAGATAAGCCATCAATGGTTGAAATCAAACCAAATCACTTTGTTT
GGGCAAACCAAGCAGAAATTGAAAAATATCAAAAAGAATTGTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (25-178)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (230-262)

3D structure

• AlphaFold DB: Q8P2L5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiF	Streptococcus thermophilus LMG 18311	82.026	99.674	0.818
amiF	Streptococcus thermophilus LMD-9	81.699	99.674	0.814
amiF	Streptococcus salivarius strain HSISS4	81.699	99.674	0.814