Detailed information NTG0021912

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: PG_RS04565
• Genome accession: NC_002950
• Coordinates: 1098576..1101479 (+)
• Length: 967 a.a.
• NCBI ID: WP_005873445.1
• Uniprot ID: Q7MVL7
• Organism: Porphyromonas gingivalis W83
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1093576..1106479

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PG_RS04545 (PG1032)	-	1094473..1095375 (+)	903	WP_010956192.1	IS982-like element IS195 family transposase	-
PG_RS04550 (PG1033)	-	1095538..1096284 (+)	747	WP_004584269.1	MlaE family ABC transporter permease	-
PG_RS04555 (PG1034)	-	1096303..1097037 (+)	735	WP_005873460.1	ABC transporter ATP-binding protein	-
PG_RS04560 (PG1035)	-	1097132..1098505 (+)	1374	WP_005873451.1	T9SS C-terminal target domain-containing protein	-
PG_RS04565 (PG1036)	uvrA	1098576..1101479 (+)	2904	WP_005873445.1	excinuclease ABC subunit UvrA	Machinery gene
PG_RS04570 (PG1037)	-	1101505..1102884 (+)	1380	WP_004584273.1	SWIM zinc finger family protein	-
PG_RS04575 (PG1038)	-	1102884..1105181 (+)	2298	WP_005873452.1	ATP-dependent helicase	-

Sequence

Protein

• Length: 967 a.a.
• Molecular weight: 108039.92 Da
• Isoelectric Point: 7.2931

>NTDB_id=21912 PG_RS04565 WP_005873445.1 1098576..1101479(+) (uvrA) [Porphyromonas gingivalis W83]
MHDTVINVKDKIARHDAVEVYGARVHNLKNIDVCIPRHSLTVITGMSGSGKSSLAFDTLFAEGQRRYIETFSAYARNFLG
GGMERPDVDEIKGLSPVISIEQKTTNRNPRSTVGTVTEVYDFFRLLYARVAEAYSYAGGKKMVKYTEEQIFHLILEKYDG
RKIALLAPVVRSRKGHYKELFERLRKKGYLHVRVDGEIREILHGMKLDRYKMHDVEVQIDKLCVASNQSKRIAESLALAM
REGEGLVMVLDSEKNEVGHFSRMMMCPDTGISYSDPAPHNFSFNSPHGYCPRCKGLGEVNLPDMDKIIPSREKSIYEGGI
EPLGKYKNNLFFWQIEALCEKYDVTIKTPLRDLPEELIEDILYGTDELLTINNKALGQSRYALSFDGVAKYILMQAEESD
ASATAQKWADQFLKTTTCPDCAGKRLNKEALSYRLAGKDIAEVNAMDIKTLIEWVDSLDEHLLDTQRAISIEILKEIRTR
LGFLKDVGLEYLTMNRAAASLSGGESQRIRLATQIGSKLVEVLYILDEPSIGLHQRDNLRLIHSLQDLRDIGNTVVVVEH
DQDMMLHADYVIDLGPRAGRHGGEVVFAGSPEEMVQANTLTADYISGRKRIEKSIGRRDGSGKTIKLFGAKGNNLQNIDV
IFPLGVFICVTGVSGSGKSTLINKTLFPAISQKLYRSLQDPMPYDRIEGLKHIDKIIAVDQSPIGRTLRSNAATYTGLFT
DIRALFVGLPESKARGYKPGRFSFNVKGGRCEVCKGNGYKTIEMNFLPDVFAPCEGCRGKRYNRETLEVRYKGKSIADVL
DMTINKAVEFFEHAPHILSKLSVLQEVGLGYIKLGQPSSTLSGGECQRVKLATELSKRDTGNTLYVLDEPTTGLHFEDVR
VLLGILNRLIERGNTVIVIEHNLDVIRCADYLIDIGPEGGAGGGQLLYQGKMEDIIECKNSYTAQFVKAELEKGRIDTVH
MNSADNI

Nucleotide

• Length: 2904 bp

>NTDB_id=21912 PG_RS04565 WP_005873445.1 1098576..1101479(+) (uvrA) [Porphyromonas gingivalis W83]
ATGCACGATACAGTTATAAACGTAAAAGACAAGATAGCTCGACACGATGCTGTCGAAGTCTATGGAGCACGGGTGCACAA
TCTGAAGAATATCGATGTGTGCATTCCGCGTCATAGCCTTACAGTCATCACTGGAATGAGTGGTAGCGGAAAGTCGTCAT
TGGCTTTCGATACCCTTTTTGCCGAAGGACAGCGACGGTACATAGAAACTTTTTCGGCTTATGCGCGGAATTTCCTCGGT
GGTGGTATGGAGCGCCCCGACGTGGACGAGATAAAAGGGCTGAGTCCGGTCATTTCCATAGAACAGAAGACGACCAATCG
GAATCCGAGATCGACTGTCGGTACCGTTACAGAGGTGTACGACTTCTTTCGTTTGCTCTATGCTCGTGTTGCTGAGGCTT
ATTCTTATGCCGGAGGAAAGAAGATGGTGAAATACACCGAGGAGCAAATCTTCCACCTCATTTTGGAAAAGTATGATGGC
CGTAAGATAGCTTTGTTAGCCCCGGTGGTTCGCTCGCGTAAGGGGCATTATAAGGAGCTATTCGAAAGGCTTCGTAAGAA
AGGCTATCTGCACGTACGCGTGGATGGTGAGATTCGCGAGATTTTGCATGGGATGAAGCTTGATCGCTATAAAATGCATG
ACGTCGAAGTGCAGATCGACAAGCTGTGCGTAGCATCGAATCAAAGCAAACGTATAGCGGAGAGCTTGGCACTGGCTATG
CGTGAAGGCGAAGGGCTTGTGATGGTGTTGGATTCGGAAAAAAACGAAGTGGGACATTTTAGTCGGATGATGATGTGTCC
TGATACGGGAATTTCGTATAGCGATCCGGCTCCGCACAATTTCAGTTTCAATTCCCCTCATGGCTATTGTCCGCGCTGTA
AGGGCTTGGGCGAAGTGAATCTGCCGGATATGGACAAGATCATTCCATCTCGTGAGAAGAGTATATACGAAGGTGGCATT
GAGCCATTGGGCAAATACAAAAACAATCTTTTCTTTTGGCAAATAGAGGCATTGTGCGAGAAGTACGATGTGACGATCAA
AACGCCTTTGCGCGATTTGCCGGAAGAGTTGATCGAGGATATCCTATATGGTACAGACGAACTACTGACCATAAACAACA
AAGCTTTGGGGCAGTCGAGGTATGCTCTCAGCTTCGATGGCGTGGCTAAGTATATATTGATGCAGGCAGAAGAATCGGAT
GCTTCGGCTACTGCGCAGAAATGGGCAGATCAGTTTCTCAAGACTACAACTTGCCCCGACTGTGCCGGCAAGCGTCTGAA
CAAAGAAGCTCTGTCCTATCGTTTGGCCGGCAAGGACATTGCAGAAGTGAATGCAATGGACATCAAGACTCTTATTGAAT
GGGTAGATTCTCTGGATGAACATCTGTTGGATACGCAACGGGCTATTTCTATAGAAATACTGAAAGAGATACGGACACGC
TTGGGGTTTCTTAAAGATGTGGGGTTGGAGTACTTGACGATGAACCGAGCTGCAGCATCCTTATCCGGAGGAGAAAGCCA
GCGTATTCGTTTGGCTACGCAGATCGGGAGCAAACTGGTTGAGGTCTTGTACATATTGGATGAACCGAGTATCGGTCTTC
ACCAAAGGGACAATCTTCGGTTGATTCATTCGCTTCAGGATTTGCGTGATATAGGCAATACAGTGGTAGTGGTGGAGCAT
GATCAGGATATGATGCTGCACGCCGACTATGTAATAGACTTAGGACCACGAGCCGGCAGACATGGTGGTGAAGTGGTGTT
TGCAGGTAGTCCGGAAGAGATGGTGCAGGCTAATACCCTGACTGCCGATTATATAAGTGGACGAAAGCGTATAGAAAAGT
CGATCGGCAGGAGAGATGGTAGTGGGAAAACGATAAAATTATTTGGAGCCAAAGGCAATAACCTGCAGAATATAGACGTT
ATCTTTCCGCTGGGGGTATTTATATGTGTTACCGGGGTCTCCGGTAGTGGGAAAAGTACATTGATCAATAAGACTCTATT
CCCTGCTATCAGCCAAAAGCTGTACCGCTCTTTGCAGGATCCGATGCCCTACGACCGCATAGAGGGGTTAAAGCATATAG
ATAAGATAATAGCCGTAGACCAAAGTCCTATCGGGCGGACGCTTAGAAGCAATGCAGCCACATATACGGGATTGTTTACC
GATATTCGCGCTCTTTTTGTCGGTCTGCCCGAGAGTAAAGCTCGTGGATATAAGCCGGGGCGTTTTTCTTTCAACGTCAA
AGGCGGACGCTGTGAGGTTTGTAAGGGTAATGGCTACAAGACGATCGAAATGAATTTTTTGCCCGATGTATTTGCTCCGT
GTGAGGGATGCCGGGGAAAGCGATACAACAGGGAGACACTCGAAGTCCGTTACAAAGGAAAATCCATTGCGGATGTTTTG
GATATGACTATCAATAAGGCTGTCGAATTTTTCGAACATGCACCTCATATTTTATCCAAGCTTTCCGTTTTACAGGAGGT
CGGTTTGGGCTATATCAAACTGGGACAACCATCCTCGACTTTGTCGGGAGGAGAGTGTCAACGTGTTAAATTAGCCACCG
AGCTGAGTAAACGTGACACGGGAAATACACTCTATGTATTAGATGAACCGACTACGGGCTTACATTTCGAAGATGTACGC
GTTTTGTTGGGGATCCTTAATCGACTGATAGAGAGAGGGAATACGGTAATAGTGATCGAACATAATTTGGATGTGATCCG
CTGTGCGGATTATTTGATTGATATAGGACCGGAGGGAGGAGCAGGTGGCGGACAGTTGCTTTACCAAGGGAAAATGGAGG
ATATAATAGAATGCAAGAATAGTTATACAGCTCAATTTGTGAAAGCCGAACTCGAAAAAGGCCGGATTGATACTGTACAC
ATGAATTCTGCAGACAATATATAA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (303-408)

• UvrA interaction domain (UvrA_inter) (146-250)

3D structure

• AlphaFold DB: Q7MVL7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	50.742	97.622	0.495
uvrA	Streptococcus pneumoniae TIGR4	50.742	97.622	0.495
uvrA	Streptococcus pneumoniae D39	50.742	97.622	0.495