Detailed information NTG0218957

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: B1761_RS08945
• Genome accession: NZ_CP019935
• Coordinates: 1656114..1657115 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain APC151
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1651114..1662115

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B1761_RS08925 (B1761_09010)	smpB	1652221..1652685 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
B1761_RS08930 (B1761_09015)	-	1652839..1654245 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
B1761_RS08935 (B1761_09020)	-	1654247..1654612 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
B1761_RS08940 (B1761_09025)	-	1654715..1655800 (-)	1086	WP_011680935.1	M24 family metallopeptidase	-
B1761_RS08945 (B1761_09030)	ccpA	1656114..1657115 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
B1761_RS08950 (B1761_09035)	-	1657174..1657371 (+)	198	WP_014608125.1	hypothetical protein	-
B1761_RS10925	-	1657477..1657701 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
B1761_RS08955 (B1761_09040)	-	1657702..1658241 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
B1761_RS08960 (B1761_09045)	-	1658254..1659369 (+)	1116	WP_011680937.1	glycerate kinase	-
B1761_RS08965 (B1761_09050)	-	1659416..1659871 (-)	456	WP_011680938.1	YueI family protein	-
B1761_RS08970 (B1761_09055)	eno	1660080..1661384 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
B1761_RS08975 (B1761_09060)	-	1661536..1661721 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=218957 B1761_RS08945 WP_004197422.1 1656114..1657115(+) (ccpA) [Streptococcus thermophilus strain APC151]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=218957 B1761_RS08945 WP_004197422.1 1656114..1657115(+) (ccpA) [Streptococcus thermophilus strain APC151]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547