Detailed information NTG0218904

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: B1761_RS01290
• Genome accession: NZ_CP019935
• Coordinates: 224750..225457 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain APC151
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 219750..230457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B1761_RS01265 (B1761_01270)	yidA	220101..220910 (+)	810	WP_011226081.1	sugar-phosphatase	-
B1761_RS01270 (B1761_01275)	-	220912..222126 (+)	1215	WP_002953123.1	aminoacyltransferase	-
B1761_RS01275 (B1761_01280)	-	222178..222539 (-)	362	Protein_227	YbaN family protein	-
B1761_RS01280 (B1761_01285)	vicX	222599..223411 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
B1761_RS01285 (B1761_01290)	vicK	223417..224757 (-)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
B1761_RS01290 (B1761_01295)	vicR	224750..225457 (-)	708	WP_011681206.1	response regulator YycF	Regulator
B1761_RS01295 (B1761_01300)	-	225984..226751 (+)	768	WP_014608372.1	amino acid ABC transporter ATP-binding protein	-
B1761_RS01300 (B1761_01305)	-	226763..227596 (+)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
B1761_RS01305 (B1761_01310)	-	227614..228312 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
B1761_RS01310 (B1761_01315)	-	228324..228974 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
B1761_RS01315 (B1761_01320)	endA	229046..229927 (-)	882	WP_014608376.1	DNA/RNA non-specific endonuclease	Machinery gene
B1761_RS01320 (B1761_01325)	-	229989..230177 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=218904 B1761_RS01290 WP_011681206.1 224750..225457(-) (vicR) [Streptococcus thermophilus strain APC151]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=218904 B1761_RS01290 WP_011681206.1 224750..225457(-) (vicR) [Streptococcus thermophilus strain APC151]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387