Detailed information NTG0021876

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: NGO_RS08605
• Genome accession: NC_002946
• Coordinates: 1690144..1690728 (+)
• Length: 194 a.a.
• NCBI ID: WP_003689924.1
• Uniprot ID: Q5F636
• Organism: Neisseria gonorrhoeae FA 1090
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1685144..1695728

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NGO_RS11425	-	1685886..1685993 (+)	108	Protein_1692	IS5/IS1182 family transposase	-
NGO_RS08575 (NGO1724)	-	1686074..1686862 (-)	789	WP_004467096.1	class I SAM-dependent methyltransferase	-
NGO_RS08580 (NGO1725)	bioH	1686859..1687608 (-)	750	WP_025456507.1	pimeloyl-ACP methyl ester esterase BioH	-
NGO_RS08585 (NGO1726)	-	1687607..1688332 (+)	726	WP_010951335.1	ComF family protein	-
NGO_RS08590 (NGO1727)	trmL	1688397..1688861 (+)	465	WP_003689916.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
NGO_RS08595 (NGO1728)	-	1688989..1689675 (+)	687	WP_003696139.1	septal ring lytic transglycosylase RlpA family protein	-
NGO_RS08600 (NGO1729)	-	1689736..1690062 (+)	327	WP_003689921.1	PepSY domain-containing protein	-
NGO_RS08605 (NGO1730)	ruvA	1690144..1690728 (+)	585	WP_003689924.1	Holliday junction branch migration protein RuvA	Machinery gene
NGO_RS11160 (NGO_1731)	-	1690728..1690865 (+)	138	WP_002235413.1	hypothetical protein	-
NGO_RS08610 (NGO1732)	-	1690892..1692748 (+)	1857	WP_010951336.1	ABC transporter ATP-binding protein	-
NGO_RS08615 (NGO1733)	rsgA	1692753..1693676 (+)	924	WP_003694242.1	ribosome small subunit-dependent GTPase A	-
NGO_RS08620 (NGO1734)	-	1693702..1694013 (+)	312	WP_003697631.1	exodeoxyribonuclease VII small subunit	-
NGO_RS08625 (NGO1735)	-	1693997..1694893 (+)	897	WP_003697633.1	polyprenyl synthetase family protein	-
NGO_RS08630 (NGO1736)	-	1695010..1695309 (-)	300	WP_010359269.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20729.99 Da
• Isoelectric Point: 6.4967

>NTDB_id=21876 NGO_RS08605 WP_003689924.1 1690144..1690728(+) (ruvA) [Neisseria gonorrhoeae FA 1090]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAASPAADETEDIVSTLLA
LGYNEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=21876 NGO_RS08605 WP_003689924.1 1690144..1690728(+) (ruvA) [Neisseria gonorrhoeae FA 1090]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGTTATGA
AGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCTCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCTCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAACGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCCCTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q5F636

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	34.951	100	0.371