Detailed information NTG0218064

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: CXP41_RS04375
• Genome accession: NZ_CP025268
• Coordinates: 820633..822654 (+)
• Length: 673 a.a.
• NCBI ID: WP_000042533.1
• Uniprot ID: Q324B3
• Organism: Escherichia coli str. K-12 substr. MG1655 strain K-12
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 815633..827654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CXP41_RS04350 (CXP41_04350)	tetR(B)	815706..816329 (+)	624	WP_000088605.1	tetracycline resistance transcriptional repressor TetR(B)	-
CXP41_RS04355 (CXP41_04355)	-	816414..817274 (+)	861	WP_000027050.1	broad-spectrum class A beta-lactamase TEM-116	-
CXP41_RS24590	-	817395..817466 (-)	72	Protein_793	hypothetical protein	-
CXP41_RS04360 (CXP41_04360)	bioF	817488..818642 (+)	1155	WP_000118826.1	8-amino-7-oxononanoate synthase	-
CXP41_RS04365 (CXP41_04365)	bioC	818629..819384 (+)	756	WP_000246761.1	malonyl-ACP O-methyltransferase BioC	-
CXP41_RS04370 (CXP41_04370)	bioD	819377..820054 (+)	678	WP_000044843.1	dethiobiotin synthase	-
CXP41_RS04375 (CXP41_04375)	uvrB	820633..822654 (+)	2022	WP_000042533.1	excinuclease ABC subunit UvrB	Machinery gene
CXP41_RS24720	-	822691..822788 (-)	98	Protein_798	hypothetical protein	-
CXP41_RS04380 (CXP41_04380)	yvcK	822846..823754 (-)	909	WP_001295302.1	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	-
CXP41_RS04385 (CXP41_04385)	moaA	824151..825140 (+)	990	WP_001350494.1	GTP 3',8-cyclase MoaA	-
CXP41_RS04390 (CXP41_04390)	moaB	825162..825674 (+)	513	WP_000084639.1	molybdenum cofactor biosynthesis protein B	-
CXP41_RS04395 (CXP41_04395)	moaC	825677..826162 (+)	486	WP_000080885.1	cyclic pyranopterin monophosphate synthase MoaC	-
CXP41_RS04400 (CXP41_04400)	moaD	826155..826400 (+)	246	WP_000598619.1	molybdopterin synthase sulfur carrier subunit	-
CXP41_RS04405 (CXP41_04405)	moaE	826402..826854 (+)	453	WP_000852296.1	molybdopterin synthase catalytic subunit MoaE	-

Sequence

Protein

• Length: 673 a.a.
• Molecular weight: 76226.06 Da
• Isoelectric Point: 4.8843

>NTDB_id=218064 CXP41_RS04375 WP_000042533.1 820633..822654(+) (uvrB) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide

• Length: 2022 bp

>NTDB_id=218064 CXP41_RS04375 WP_000042533.1 820633..822654(+) (uvrB) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCAGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTTTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
TTTCATTGAGAAAGATGCCTCGGTTAACGAACATATTGAGCAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATTCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGCGTTCGTGGCGAGGTGATAGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACACCGCGCGAGCGCATCGTACAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGCAAAGTGCTGTTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCGGGGATTGAAAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTCGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTTAAGTTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTTGACCCGATTATCGAAGTGCGGCC
GGTGGCGACACAGGTTGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTCACCACAC
TGACCAAGCGGATGGCGGAAGATCTTACCGAATATCTCGAAGAACATGGCGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTGCTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTGTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGTGAGAAACAGCAGAAGTACAACGAGGAACACGGAATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAAATCCATGAGCTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGCTGCGTGA
GCTGTTTATCGCGGCATCGTAA

Domains

Predicted by InterProScan.

• UvrB interaction domain (UvrB_inter) (159-249)

• UvrB/uvrC motif (UVR) (634-667)

• Ultra-violet resistance protein B (UvrB) (552-593)

• Type III restriction enzyme, res subunit (ResIII) (13-92)

• Helicase conserved C-terminal domain (Helicase_C) (436-544)

3D structure

• AlphaFold DB: Q324B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae TIGR4	56.372	99.108	0.559
uvrB	Streptococcus pneumoniae R6	56.222	99.108	0.557
uvrB	Streptococcus pneumoniae D39	56.222	99.108	0.557