Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BH100B_RS19260 Genome accession   NZ_CP025251
Coordinates   3767185..3767817 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain BH100 substr. MG2017     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3762185..3772817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BH100B_RS19230 (BH100B_03764) yheS 3762354..3764267 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  BH100B_RS19235 (BH100B_03765) yheT 3764267..3765289 (+) 1023 WP_000057389.1 hydrolase -
  BH100B_RS19240 (BH100B_03766) yheU 3765283..3765501 (+) 219 WP_000907085.1 YheU family protein -
  BH100B_RS19245 (BH100B_03767) prkB 3765555..3766424 (+) 870 WP_001274680.1 phosphoribulokinase -
  BH100B_RS19250 (BH100B_03768) yhfA 3766479..3766883 (-) 405 WP_001148908.1 OsmC family protein -
  BH100B_RS19260 (BH100B_03770) crp 3767185..3767817 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BH100B_RS19265 (BH100B_03771) yhfK 3767868..3769958 (+) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  BH100B_RS19270 (BH100B_03772) argD 3770036..3771256 (-) 1221 WP_000963809.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BH100B_RS19275 (BH100B_03773) pabA 3771342..3771905 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  BH100B_RS19280 (BH100B_03774) fic 3771937..3772539 (-) 603 WP_001280615.1 putative adenosine monophosphate-protein transferase Fic -
  BH100B_RS19285 (BH100B_03775) yhfG 3772529..3772696 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=217825 BH100B_RS19260 WP_000242755.1 3767185..3767817(+) (crp) [Escherichia coli strain BH100 substr. MG2017]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=217825 BH100B_RS19260 WP_000242755.1 3767185..3767817(+) (crp) [Escherichia coli strain BH100 substr. MG2017]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467