Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CWI22_RS03595 Genome accession   NZ_CP025053
Coordinates   728490..729134 (-) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa strain PB354     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 723490..734134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI22_RS03565 (CWI22_03565) - 723939..724991 (+) 1053 WP_031633763.1 pyocin knob domain-containing protein -
  CWI22_RS03570 (CWI22_03570) - 724991..725293 (+) 303 WP_003113177.1 hypothetical protein -
  CWI22_RS03575 (CWI22_03575) - 725290..725520 (+) 231 WP_003161916.1 hypothetical protein -
  CWI22_RS03580 (CWI22_03580) - 725939..726544 (+) 606 WP_023098405.1 aminodeoxychorismate/anthranilate synthase component II -
  CWI22_RS03585 (CWI22_03585) trpD 726546..727595 (+) 1050 WP_003085203.1 anthranilate phosphoribosyltransferase -
  CWI22_RS03590 (CWI22_03590) trpC 727592..728428 (+) 837 WP_003085205.1 indole-3-glycerol phosphate synthase TrpC -
  CWI22_RS03595 (CWI22_03595) crp 728490..729134 (-) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  CWI22_RS03600 (CWI22_03600) - 729406..729828 (+) 423 WP_003085219.1 OsmC family protein -
  CWI22_RS03605 (CWI22_03605) speD 730148..730942 (+) 795 WP_003085223.1 adenosylmethionine decarboxylase -
  CWI22_RS03610 (CWI22_03610) coq7 730997..731644 (-) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  CWI22_RS03615 (CWI22_03615) - 731744..732082 (-) 339 WP_003085225.1 histidine triad nucleotide-binding protein -
  CWI22_RS03620 (CWI22_03620) - 732161..733642 (+) 1482 WP_003101642.1 AAA family ATPase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=216960 CWI22_RS03595 WP_003085214.1 728490..729134(-) (crp) [Pseudomonas aeruginosa strain PB354]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=216960 CWI22_RS03595 WP_003085214.1 728490..729134(-) (crp) [Pseudomonas aeruginosa strain PB354]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGCGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAATT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTGGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGGAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505