Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CWI33_RS11485 Genome accession   NZ_CP025048
Coordinates   2243840..2244472 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain SC516     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2238840..2249472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI33_RS11455 (CWI33_11455) yheS 2239009..2240922 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CWI33_RS11460 (CWI33_11460) yheT 2240922..2241944 (+) 1023 WP_072643357.1 hydrolase -
  CWI33_RS11465 (CWI33_11465) yheU 2241938..2242156 (+) 219 WP_000907085.1 YheU family protein -
  CWI33_RS11470 (CWI33_11470) prkB 2242210..2243079 (+) 870 WP_001274680.1 phosphoribulokinase -
  CWI33_RS11475 (CWI33_11475) yhfA 2243134..2243538 (-) 405 WP_001148908.1 OsmC family protein -
  CWI33_RS11485 (CWI33_11485) crp 2243840..2244472 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CWI33_RS11490 (CWI33_11490) yhfK 2244523..2246613 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CWI33_RS11495 (CWI33_11495) argD 2246676..2247899 (-) 1224 WP_000963789.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CWI33_RS11500 (CWI33_11500) pabA 2247985..2248548 (-) 564 WP_072643356.1 aminodeoxychorismate synthase component 2 -
  CWI33_RS11505 (CWI33_11505) fic 2248580..2249182 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CWI33_RS11510 (CWI33_11510) yhfG 2249172..2249339 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=216706 CWI33_RS11485 WP_000242755.1 2243840..2244472(+) (crp) [Escherichia coli strain SC516]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=216706 CWI33_RS11485 WP_000242755.1 2243840..2244472(+) (crp) [Escherichia coli strain SC516]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467