Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   NMA_RS11170 Genome accession   NC_003116
Coordinates   2139504..2140199 (-) Length   231 a.a.
NCBI ID   WP_002215704.1    Uniprot ID   Q7DDR6
Organism   Neisseria meningitidis Z2491     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2129942..2141029 2139504..2140199 within 0


Gene organization within MGE regions


Location: 2129942..2141029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA_RS14745 (NMA2186) - 2129942..2130400 (-) 459 WP_002234522.1 hypothetical protein -
  NMA_RS11125 (NMA2187) comE 2130512..2130976 (-) 465 WP_010981251.1 helix-hairpin-helix domain-containing protein Machinery gene
  NMA_RS11160 (NMA2189) - 2136776..2137582 (-) 807 WP_002245849.1 cytochrome C assembly family protein -
  NMA_RS11165 (NMA2190) ffh 2137803..2139173 (+) 1371 WP_002245848.1 signal recognition particle protein -
  NMA_RS11170 (NMA2191) dsbA2 2139504..2140199 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  NMA_RS11175 (NMA2192) - 2140370..2141029 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25419.90 Da        Isoelectric Point: 5.1502

>NTDB_id=21667 NMA_RS11170 WP_002215704.1 2139504..2140199(-) (dsbA2) [Neisseria meningitidis Z2491]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=21667 NMA_RS11170 WP_002215704.1 2139504..2140199(-) (dsbA2) [Neisseria meningitidis Z2491]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCCGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7DDR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

100

100

1
  dsbA1 Neisseria meningitidis MC58

71.245

100

0.719

Multiple sequence alignment