Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NMA_RS11125 Genome accession   NC_003116
Coordinates   2130512..2130976 (-) Length   154 a.a.
NCBI ID   WP_010981251.1    Uniprot ID   -
Organism   Neisseria meningitidis Z2491     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2129942..2141029 2130512..2130976 within 0
IS/Tn 2129169..2129822 2130512..2130976 flank 690


Gene organization within MGE regions


Location: 2129169..2141029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA_RS11115 (NMA2185) - 2129169..2129822 (-) 654 WP_002245850.1 IS1595 family transposase -
  NMA_RS14745 (NMA2186) - 2129942..2130400 (-) 459 WP_002234522.1 hypothetical protein -
  NMA_RS11125 (NMA2187) comE 2130512..2130976 (-) 465 WP_010981251.1 helix-hairpin-helix domain-containing protein Machinery gene
  NMA_RS11160 (NMA2189) - 2136776..2137582 (-) 807 WP_002245849.1 cytochrome C assembly family protein -
  NMA_RS11165 (NMA2190) ffh 2137803..2139173 (+) 1371 WP_002245848.1 signal recognition particle protein -
  NMA_RS11170 (NMA2191) dsbA2 2139504..2140199 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  NMA_RS11175 (NMA2192) - 2140370..2141029 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16457.69 Da        Isoelectric Point: 10.7894

>NTDB_id=21666 NMA_RS11125 WP_010981251.1 2130512..2130976(-) (comE) [Neisseria meningitidis Z2491]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPALPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=21666 NMA_RS11125 WP_010981251.1 2130512..2130976(-) (comE) [Neisseria meningitidis Z2491]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGTGCGCCCGCACCAAAAGGCCCGGCAAAACCGGCTCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment