Detailed information NTG0216545

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: BJN19_RS14645
• Genome accession: NZ_CP019590
• Coordinates: 2775127..2776014 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain C2406
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2770127..2781014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJN19_RS14610 (BJN19_14630)	-	2770146..2770238 (+)	93	WP_010956583.1	hypothetical protein	-
BJN19_RS14615 (BJN19_14635)	-	2770346..2770843 (-)	498	WP_001065268.1	glutathione peroxidase	-
BJN19_RS14620 (BJN19_14640)	-	2770853..2771113 (-)	261	WP_001789910.1	hypothetical protein	-
BJN19_RS14630 (BJN19_14650)	-	2771495..2771608 (-)	114	WP_001791776.1	hypothetical protein	-
BJN19_RS14635 (BJN19_14655)	-	2772267..2774267 (-)	2001	WP_000776751.1	ABC transporter permease	-
BJN19_RS14640 (BJN19_14660)	-	2774264..2775019 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
BJN19_RS14645 (BJN19_14665)	braS	2775127..2776014 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
BJN19_RS14650 (BJN19_14670)	braR	2776025..2776690 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
BJN19_RS14655 (BJN19_14675)	-	2776716..2776916 (-)	201	WP_000604728.1	hypothetical protein	-
BJN19_RS14660 (BJN19_14680)	-	2777114..2778538 (+)	1425	WP_000953744.1	alkaline phosphatase	-
BJN19_RS15495 (BJN19_14685)	-	2778598..2778699 (-)	102	WP_000731972.1	SE2200 family small protein	-
BJN19_RS14670 (BJN19_14690)	-	2778821..2779276 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
BJN19_RS14675 (BJN19_14695)	-	2779521..2780282 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=216545 BJN19_RS14645 WP_000143419.1 2775127..2776014(-) (braS) [Staphylococcus aureus strain C2406]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=216545 BJN19_RS14645 WP_000143419.1 2775127..2776014(-) (braS) [Staphylococcus aureus strain C2406]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997