Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   NMA_RS05540 Genome accession   NC_003116
Coordinates   1054773..1055438 (+) Length   221 a.a.
NCBI ID   WP_010981159.1    Uniprot ID   A0A0U1RIG8
Organism   Neisseria meningitidis Z2491     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1049773..1060438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA_RS05520 (NMA1101) - 1049885..1050217 (+) 333 WP_002213854.1 hypothetical protein -
  NMA_RS05525 (NMA1102) - 1050549..1051058 (+) 510 WP_002213852.1 isoprenylcysteine carboxyl methyltransferase family protein -
  NMA_RS05530 (NMA1104) - 1052308..1052895 (-) 588 WP_002246908.1 superoxide dismutase -
  NMA_RS05535 (NMA1105) dnaB 1053058..1054464 (+) 1407 WP_002238995.1 replicative DNA helicase -
  NMA_RS05540 (NMA1106) pilH 1054773..1055438 (+) 666 WP_010981159.1 GspH/FimT family pseudopilin Machinery gene
  NMA_RS05545 (NMA1107) pilV 1055468..1056082 (+) 615 WP_010981160.1 type IV pilus modification protein PilV Machinery gene
  NMA_RS05550 (NMA1108) pilJ 1056079..1057077 (+) 999 WP_010981161.1 PilW family protein Machinery gene
  NMA_RS05555 (NMA1109) pilK 1057056..1057649 (+) 594 WP_010981162.1 pilus assembly PilX family protein Machinery gene
  NMA_RS05560 (NMA1110) pilX 1057654..1058127 (+) 474 WP_002245541.1 PilX family type IV pilin Machinery gene
  NMA_RS05565 (NMA1111) - 1059491..1059919 (-) 429 Protein_1052 AzlC family ABC transporter permease -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24564.05 Da        Isoelectric Point: 9.8992

>NTDB_id=21645 NMA_RS05540 WP_010981159.1 1054773..1055438(+) (pilH) [Neisseria meningitidis Z2491]
MCTRKQQGFTLTELLIVMVIAAVMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTVN
NKCDSGKKGQGMLAFGDKNGNKTYDGDAADVFLRSVVLNDTDDSRINYAFNHIAFGSSQPTADRVVWTFNQNGTFGYTKG
QHLTSKSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 666 bp        

>NTDB_id=21645 NMA_RS05540 WP_010981159.1 1054773..1055438(+) (pilH) [Neisseria meningitidis Z2491]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCGTTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGGTCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGACATATGACGGCGA
TGCGGCGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTATGCCTTCAACCATATCG
CTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAAGGC
CAGCATCTTACAAGCAAATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACGATA
GGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1RIG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.909

99.548

0.855

Multiple sequence alignment