Detailed information NTG0021648

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SA_RS08730
• Genome accession: NC_002745
• Coordinates: 1771160..1772434 (+)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus subsp. aureus N315
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1766160..1777434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA_RS08710	-	1767484..1767579 (+)	96	WP_031761395.1	hypothetical protein	-
SA_RS08715 (SA1546)	-	1767540..1768670 (-)	1131	WP_000721699.1	HAD family hydrolase	-
SA_RS08720 (SA1547)	nagE	1768777..1770243 (-)	1467	WP_000276367.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
SA_RS08725 (SA1548)	-	1770371..1770988 (-)	618	WP_000287588.1	lysophospholipid acyltransferase family protein	-
SA_RS08730 (SA1549)	htrA	1771160..1772434 (+)	1275	WP_001279338.1	S1C family serine protease	Regulator
SA_RS08735 (SA1550)	tyrS	1772528..1773790 (-)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
SA_RS08740 (SA1551)	-	1774172..1775077 (+)	906	WP_000184370.1	transglycosylase domain-containing protein	-
SA_RS08745	-	1775057..1775149 (-)	93	WP_031761401.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=21648 SA_RS08730 WP_001279338.1 1771160..1772434(+) (htrA) [Staphylococcus aureus subsp. aureus N315]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=21648 SA_RS08730 WP_001279338.1 1771160..1772434(+) (htrA) [Staphylococcus aureus subsp. aureus N315]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37