Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   BZG42_RS02050 Genome accession   NZ_CP019557
Coordinates   404024..405316 (+) Length   430 a.a.
NCBI ID   WP_155996311.1    Uniprot ID   -
Organism   Streptococcus sp. DAT741     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 399024..410316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS02020 (BZG42_02000) - 399165..400565 (+) 1401 WP_120171352.1 Cof-type HAD-IIB family hydrolase -
  BZG42_RS02025 (BZG42_02005) - 400567..400938 (+) 372 WP_024532771.1 S1 RNA-binding domain-containing protein -
  BZG42_RS02030 (BZG42_02010) - 401013..401333 (+) 321 WP_120171198.1 transposase -
  BZG42_RS02035 (BZG42_02015) - 401330..402214 (+) 885 WP_159780061.1 IS3 family transposase -
  BZG42_RS02040 (BZG42_02020) cysK 402316..403242 (-) 927 WP_024533095.1 cysteine synthase A -
  BZG42_RS02045 (BZG42_02025) - 403335..403967 (-) 633 WP_155996310.1 YigZ family protein -
  BZG42_RS02050 (BZG42_02030) comFA/cflA 404024..405316 (+) 1293 WP_155996311.1 DEAD/DEAH box helicase Machinery gene
  BZG42_RS02055 (BZG42_02035) - 405309..405974 (+) 666 WP_024533092.1 ComF family protein -
  BZG42_RS02060 (BZG42_02040) raiA 406051..406593 (+) 543 WP_155996312.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 49037.58 Da        Isoelectric Point: 9.3065

>NTDB_id=216210 BZG42_RS02050 WP_155996311.1 404024..405316(+) (comFA/cflA) [Streptococcus sp. DAT741]
MNELQDYYGRLFTRNQLTAVERERAQIIPSITEKKTCFRCGTPFEEEYQLPNGAFYCRTCLLLGRVRSDEKLYYFPQRDF
PKNTCLQWKGRLTNWQQTISDALCANVEKRQATLVHAVTGAGKTEMIYHTVASVIDSGGAVCLASPRIDVCIELYKRLQQ
DFSVPISLLHGESEAYFRTPMVIATTHQLLKFYRAFDLLLIDEVDAFPYADNPVLYRAVDNAVKPDGVQVFLTATSTDQL
EKKIKAGKLERLSLPRRFHGNPLVVPQKIWFSQFEQYLKKGRLTPKLAKVIQHQRKTGYPLLIFVPEIGKGMEFTKVVKK
AFPNENIGFVSSQTENRLEIVEGFRNKNITILISTTILERGVTFPCVDVFVIQANHYLYSSSSLVQIAGRVGRSQERPTG
LLHFFHEGSTRAIEKSIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=216210 BZG42_RS02050 WP_155996311.1 404024..405316(+) (comFA/cflA) [Streptococcus sp. DAT741]
ATGAATGAATTACAAGATTACTATGGAAGACTATTTACCAGGAATCAACTAACAGCAGTTGAGAGGGAAAGAGCGCAGAT
AATTCCAAGTATTACAGAGAAAAAAACTTGTTTCAGATGCGGAACTCCCTTTGAAGAAGAATACCAGTTGCCAAATGGAG
CTTTTTATTGTCGAACCTGTTTGCTTTTAGGAAGGGTACGCTCGGACGAAAAACTTTACTATTTTCCACAGAGAGATTTT
CCTAAAAATACCTGCTTACAGTGGAAAGGACGACTGACCAATTGGCAACAAACCATTTCTGATGCTCTTTGCGCCAATGT
TGAGAAAAGGCAAGCTACGCTGGTTCATGCAGTAACAGGAGCTGGAAAAACAGAGATGATATATCATACAGTAGCTTCTG
TTATTGATAGTGGTGGAGCAGTTTGTTTAGCTAGTCCACGAATTGATGTTTGTATCGAACTCTATAAACGCTTGCAGCAG
GATTTTTCAGTTCCAATTAGTCTCTTGCACGGAGAATCAGAGGCCTACTTTAGAACCCCCATGGTCATTGCTACAACTCA
TCAGCTCTTAAAATTTTATCGTGCTTTTGATTTGCTTTTGATTGATGAAGTAGATGCCTTTCCATACGCAGATAATCCTG
TTCTTTATCGGGCAGTAGACAATGCAGTAAAACCAGATGGTGTACAGGTATTTTTGACAGCTACTTCAACAGATCAACTT
GAGAAAAAGATAAAAGCAGGAAAACTAGAACGCCTTAGTTTGCCCAGACGATTTCATGGCAATCCACTAGTAGTACCACA
AAAAATTTGGTTCAGCCAATTTGAACAGTATCTAAAGAAAGGTAGATTGACCCCTAAGCTGGCAAAGGTTATCCAGCATC
AGCGAAAGACAGGCTATCCCTTGCTAATATTTGTTCCAGAAATCGGAAAAGGGATGGAATTTACAAAGGTAGTCAAAAAA
GCATTTCCTAATGAAAACATTGGTTTTGTTTCCAGTCAGACAGAAAATCGCCTGGAGATAGTAGAAGGATTTCGCAATAA
AAACATCACCATTTTAATCTCAACCACCATTCTTGAACGCGGTGTAACCTTCCCTTGTGTTGATGTCTTTGTTATTCAGG
CCAATCATTATCTCTATAGTTCATCTAGTTTAGTTCAAATAGCAGGTCGAGTTGGTCGCAGCCAAGAACGACCAACAGGG
CTTCTACATTTTTTTCACGAAGGAAGCACGCGGGCGATTGAAAAGTCCATCGCTGAAATCAAACAAATGAATAAGGAGGC
AGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(92-235)

Helicase conserved C-terminal domain (Helicase_C)

(291-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

64.554

99.07

0.64
  comFA/cflA Streptococcus pneumoniae D39

64.554

99.07

0.64
  comFA/cflA Streptococcus pneumoniae R6

64.554

99.07

0.64
  comFA/cflA Streptococcus pneumoniae TIGR4

64.554

99.07

0.64
  comFA/cflA Streptococcus mitis NCTC 12261

63.85

99.07

0.633
  comFA/cflA Streptococcus mitis SK321

63.146

99.07

0.626
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.326

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

38.462

99.767

0.384

Multiple sequence alignment