Detailed information NTG0216152

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: CWQ23_RS01070
• Genome accession: NZ_CP025026
• Coordinates: 176071..176532 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SGEHI2015-113
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 171071..181532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWQ23_RS01035 (CWQ23_01035)	-	172686..173051 (+)	366	WP_000285373.1	DUF1033 family protein	-
CWQ23_RS01045 (CWQ23_01045)	comGA	173224..174195 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
CWQ23_RS01050 (CWQ23_01050)	comGB	174089..175132 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
CWQ23_RS01055 (CWQ23_01055)	comGC/cglC	175129..175458 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
CWQ23_RS01060 (CWQ23_01060)	comGD	175433..175846 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
CWQ23_RS01065 (CWQ23_01065)	comGE	175818..176117 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
CWQ23_RS01070 (CWQ23_01070)	comGF	176071..176532 (+)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
CWQ23_RS01075 (CWQ23_01075)	comGG	176510..176881 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
CWQ23_RS01080 (CWQ23_01080)	comGH	176996..177970 (+)	975	WP_001008574.1	N-6 DNA methylase	Machinery gene
CWQ23_RS01085 (CWQ23_01085)	-	178002..179195 (+)	1194	WP_000047534.1	acetate kinase	-
CWQ23_RS01090 (CWQ23_01090)	-	179347..179553 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
CWQ23_RS01095 (CWQ23_01095)	-	179612..179749 (+)	138	WP_001865900.1	hypothetical protein	-
CWQ23_RS01100 (CWQ23_01100)	-	179790..180245 (+)	456	WP_000905673.1	hypothetical protein	-
CWQ23_RS01105 (CWQ23_01105)	-	180314..180979 (+)	666	WP_000008113.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=216152 CWQ23_RS01070 WP_001874812.1 176071..176532(+) (comGF) [Streptococcus agalactiae strain SGEHI2015-113]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=216152 CWQ23_RS01070 WP_001874812.1 176071..176532(+) (comGF) [Streptococcus agalactiae strain SGEHI2015-113]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373