Detailed information NTG0215875

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: CVT30_RS06740
• Genome accession: NZ_CP024989
• Coordinates: 1579481..1580122 (-)
• Length: 213 a.a.
• NCBI ID: WP_045556539.1
• Uniprot ID: -
• Organism: Streptomyces sp. AMCC400023
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1574481..1585122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CVT30_RS06725 (CVT30_06850)	-	1574666..1576123 (-)	1458	WP_093790121.1	aldehyde dehydrogenase family protein	-
CVT30_RS06730 (CVT30_06855)	-	1576795..1577874 (-)	1080	WP_272897491.1	aldehyde dehydrogenase family protein	-
CVT30_RS46655	-	1577847..1578278 (-)	432	WP_272897492.1	aldehyde dehydrogenase family protein	-
CVT30_RS06735 (CVT30_06860)	-	1578424..1579335 (-)	912	WP_237313003.1	SDR family oxidoreductase	-
CVT30_RS06740 (CVT30_06865)	vraR	1579481..1580122 (-)	642	WP_045556539.1	response regulator transcription factor	Regulator
CVT30_RS06745 (CVT30_06870)	-	1580149..1581765 (-)	1617	WP_237313004.1	GAF domain-containing sensor histidine kinase	-
CVT30_RS06750 (CVT30_06875)	-	1582142..1583773 (+)	1632	WP_193379844.1	AMP-binding protein	-
CVT30_RS06755 (CVT30_06880)	-	1584060..1584722 (-)	663	WP_045556536.1	GntR family transcriptional regulator	-

Sequence

Protein

• Length: 213 a.a.
• Molecular weight: 22712.19 Da
• Isoelectric Point: 5.9441

>NTDB_id=215875 CVT30_RS06740 WP_045556539.1 1579481..1580122(-) (vraR) [Streptomyces sp. AMCC400023]
MLIVDDHAVVRRGIRAYLEVLGDMEVAAEAADGQEALARLDAMAAHGELPDVVLIDLLMPRMDGPTAIGLIKEHHPGVRV
VVLTSFGEMERVHAALAQGAAGYLLKDADAGEVVSAIRAAARGEVFLDPAVARGLTQEIVAPPTGLGALTTRERDVLVLV
AEGRSNQQIADELVISERTARTHVSNVLRKLRLTSRTQAALFAVRQGLVQPRG

Nucleotide

• Length: 642 bp

>NTDB_id=215875 CVT30_RS06740 WP_045556539.1 1579481..1580122(-) (vraR) [Streptomyces sp. AMCC400023]
GTGCTGATCGTGGACGACCACGCCGTCGTACGCCGTGGCATCCGCGCCTACCTGGAAGTCCTGGGCGACATGGAGGTCGC
CGCGGAGGCGGCCGACGGGCAGGAGGCGCTCGCCCGGCTGGACGCGATGGCGGCCCACGGCGAGCTGCCGGACGTGGTGC
TGATCGACCTGCTCATGCCCAGGATGGACGGCCCCACCGCGATCGGGCTGATCAAGGAACACCACCCCGGGGTACGGGTC
GTGGTGCTCACCAGCTTCGGCGAGATGGAGCGCGTCCACGCCGCCCTCGCCCAGGGGGCCGCGGGTTACCTGCTCAAGGA
CGCGGATGCCGGCGAGGTGGTCTCCGCGATCCGCGCGGCGGCACGCGGAGAGGTCTTCCTCGACCCCGCGGTCGCCCGAG
GGCTCACCCAGGAGATCGTGGCGCCGCCGACCGGGCTCGGTGCACTCACCACCCGCGAGCGTGATGTCCTCGTCCTCGTC
GCCGAGGGACGGTCCAACCAGCAGATCGCCGACGAACTGGTGATCAGCGAGCGCACGGCCCGCACACATGTGAGCAATGT
GCTGCGCAAGCTGCGCCTCACGTCACGGACCCAGGCGGCGCTGTTCGCCGTACGGCAGGGACTGGTACAGCCGCGCGGCT
GA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, luxR family (GerE) (149-203)

• Response regulator receiver domain (Response_reg) (2-117)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	41.627	98.122	0.408
degU	Bacillus subtilis subsp. subtilis str. 168	36.681	100	0.394