Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CV098_RS02450 Genome accession   NZ_CP024958
Coordinates   479849..481927 (+) Length   692 a.a.
NCBI ID   WP_017864174.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain G423     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 474849..486927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV098_RS02430 (CV098_02430) - 476794..477264 (-) 471 WP_003130820.1 Rrf2 family transcriptional regulator -
  CV098_RS02435 (CV098_02435) gap 477437..478450 (+) 1014 WP_003130818.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  CV098_RS02440 (CV098_02440) def 478593..479228 (-) 636 WP_017864173.1 peptide deformylase -
  CV098_RS02445 (CV098_02445) - 479382..479858 (+) 477 WP_032947921.1 RNA pyrophosphohydrolase -
  CV098_RS02450 (CV098_02450) uvrB 479849..481927 (+) 2079 WP_017864174.1 excinuclease ABC subunit UvrB Machinery gene
  CV098_RS02455 (CV098_02455) - 482123..482932 (+) 810 WP_010905441.1 ABC transporter substrate-binding protein -
  CV098_RS02460 (CV098_02460) - 482947..484110 (+) 1164 WP_017864175.1 M20 family metallopeptidase -
  CV098_RS02465 (CV098_02465) fabZ 484134..484589 (-) 456 WP_017864176.1 3-hydroxyacyl-ACP dehydratase FabZ -
  CV098_RS02470 (CV098_02470) fabI 484865..485617 (+) 753 WP_012897290.1 enoyl-ACP reductase FabI -

Sequence

Protein


Download         Length: 692 a.a.        Molecular weight: 79132.40 Da        Isoelectric Point: 4.5327

>NTDB_id=215696 CV098_RS02450 WP_017864174.1 479849..481927(+) (uvrB) [Lactococcus lactis subsp. lactis strain G423]
MAIERITDNKFELVSKYEPAGDQGEAIAELVDNIENGEKAQILRGATGTGKTYTMSQVIARTGKPTLVMAHNKTLAGQLY
SEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEY
QDSVVSLRPGQEISRDQLLNDLVGIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRIREIEVLTGQV
LGEVDHLAIFPATHFMTNDDRMEESIAKIEAELEEQLKVFRSEGKLLEAQRLEQRTNYDIEMLREMGYCNGVENYSRHMD
GREEGEPPYTLLDFFPDDFMIMIDESHMTMGQVKGMYNGDRARKEMLCNYGFRLPSALDNRPLKREEFESHVHQIVYVSA
TPGDYEMEQTDTIVEQIIRPTGLLDPVVEVRPMMGQIDDLVGEIHERAEKNERVFVTTLTKKMSEDLTAYFKEMGIKVKY
MHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVILYSD
MAKALDENDPVDKEILDSGYYTEYEGQKYKITRSMKHAMDETARRREIQMAYNEEHGITPQTIKKEIRDLIAITKKTDSG
EIEEVDASAMTKKERKALVKKLEKEMQQAASALDFEGAAQLRDMVLELRAMD

Nucleotide


Download         Length: 2079 bp        

>NTDB_id=215696 CV098_RS02450 WP_017864174.1 479849..481927(+) (uvrB) [Lactococcus lactis subsp. lactis strain G423]
ATGGCTATAGAAAGAATAACAGATAATAAATTTGAACTTGTTTCAAAATATGAGCCAGCCGGTGACCAAGGTGAGGCGAT
TGCTGAGTTAGTAGATAATATTGAGAATGGGGAAAAAGCTCAAATTTTACGTGGAGCAACAGGAACAGGGAAAACGTACA
CCATGAGTCAAGTGATTGCACGGACAGGTAAACCTACTCTTGTTATGGCTCATAATAAAACACTGGCTGGTCAATTATAC
AGTGAATTTAAAGAGTTTTTTCCAAATAATGCAGTCGAGTATTTCGTATCCTACTATGATTATTATCAACCCGAAGCCTA
TGTTCCAAGTTCTGACACCTATATTGAAAAAGACAGTTCGGTCAATGATGAAATTGACAAATTGCGTCACAGTGCGACCT
CAAGCTTATTGGAACGTAATGATGTGATTGTTGTGGCCTCAGTTTCTTGTATTTATGGTTTGGGTTCACCCAAAGAGTAT
CAAGATTCGGTGGTTTCATTGCGCCCAGGTCAAGAAATTTCTCGTGACCAACTTTTAAATGATTTGGTAGGAATTCAATT
TGAGCGAAATGATATTGACTTTCAACGGGGCTGTTTCCGAGTTCGTGGGGATGTTGTAGAAGTTTTTCCAGCCTCTCGTG
ATGAACATGCCTTTCGTGTTGAATTTTTCGGTGATGAAATTGACCGTATCCGTGAAATTGAAGTTTTGACCGGACAAGTT
TTAGGTGAAGTAGACCATTTGGCAATTTTCCCAGCGACACATTTCATGACAAATGATGACCGTATGGAAGAATCAATTGC
CAAGATAGAAGCAGAATTAGAAGAACAATTAAAAGTTTTCCGCTCAGAAGGAAAACTTCTTGAGGCTCAACGTTTAGAAC
AAAGAACCAACTACGATATCGAAATGCTCCGTGAAATGGGTTATTGTAATGGGGTCGAAAACTATTCACGTCATATGGAT
GGGCGCGAGGAAGGCGAACCTCCGTATACTTTGCTTGATTTCTTTCCTGATGATTTCATGATTATGATTGATGAATCACA
CATGACAATGGGTCAAGTAAAAGGAATGTATAACGGTGACAGAGCCCGTAAAGAAATGCTTTGTAATTATGGATTCCGCC
TGCCTTCAGCCCTCGATAACCGTCCTTTAAAAAGAGAAGAATTTGAAAGTCATGTGCATCAAATTGTTTATGTTTCAGCA
ACCCCTGGGGATTATGAGATGGAGCAGACCGATACCATTGTTGAACAAATTATTCGTCCAACAGGTCTATTAGATCCTGT
CGTAGAAGTTCGACCAATGATGGGACAAATCGATGATTTAGTTGGTGAAATTCATGAACGAGCTGAGAAAAACGAACGAG
TATTCGTCACGACTTTGACTAAAAAGATGTCAGAAGATTTGACTGCCTATTTCAAGGAAATGGGGATAAAAGTTAAATAT
ATGCACTCGGATATCAAAACATTAGAACGAACCGAAATTATTCGGGATTTGCGTTTAGGAGTCTTTGATGTTCTGGTGGG
AATAAATCTGCTTCGCGAAGGGATTGACGTGCCAGAAGTTTCTTTAGTCGCGATTTTGGATGCTGATAAAGAAGGATTTT
TACGTAATGAGCGTGGCTTGATTCAGACCATTGGTCGTGCAGCACGTAATAGTGAAGGTCATGTTATTCTTTATTCTGAT
ATGGCTAAAGCCCTTGATGAAAATGATCCTGTGGATAAAGAAATCTTAGATAGTGGTTATTATACAGAATACGAGGGTCA
AAAGTATAAAATAACGCGTTCAATGAAACATGCGATGGATGAAACAGCCCGTCGGCGTGAAATTCAAATGGCTTATAATG
AAGAACATGGAATCACACCTCAAACGATCAAAAAAGAAATTCGTGATTTGATTGCCATTACTAAGAAAACTGATTCTGGT
GAGATTGAAGAAGTTGATGCAAGTGCGATGACTAAGAAAGAACGTAAAGCATTAGTCAAAAAACTTGAAAAAGAAATGCA
ACAAGCGGCTAGCGCCCTCGACTTTGAAGGAGCTGCTCAGTTACGTGATATGGTATTAGAATTACGTGCAATGGATTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(443-550)

UvrB interaction domain (UvrB_inter)

(165-255)

Type III restriction enzyme, res subunit (ResIII)

(19-144)

Ultra-violet resistance protein B (UvrB)

(590-628)

UvrB/uvrC motif (UVR)

(657-690)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae D39

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae TIGR4

81.884

99.711

0.816