Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   CV098_RS01890 Genome accession   NZ_CP024958
Coordinates   377297..378739 (-) Length   480 a.a.
NCBI ID   WP_012897229.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain G423     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 372297..383739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV098_RS01865 (CV098_01865) nox 372331..373671 (+) 1341 WP_017864127.1 H2O-forming NADH oxidase -
  CV098_RS01870 (CV098_01870) - 373761..374150 (+) 390 WP_017864128.1 single-stranded DNA-binding protein -
  CV098_RS01875 (CV098_01875) groES 374270..374554 (+) 285 WP_017864129.1 co-chaperone GroES -
  CV098_RS01880 (CV098_01880) groL 374642..376270 (+) 1629 WP_003131585.1 chaperonin GroEL -
  CV098_RS01885 (CV098_01885) vicX 376316..377128 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  CV098_RS01890 (CV098_01890) vicK 377297..378739 (-) 1443 WP_012897229.1 sensor histidine kinase Regulator
  CV098_RS01895 (CV098_01895) yycF 378732..379433 (-) 702 WP_003131580.1 response regulator YycF -
  CV098_RS01900 (CV098_01900) tmk 379611..380246 (+) 636 WP_012897230.1 dTMP kinase -
  CV098_RS01905 (CV098_01905) - 380379..381239 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  CV098_RS01910 (CV098_01910) yaaT 381291..382073 (+) 783 WP_017864130.1 PSP1 domain-containing protein Regulator
  CV098_RS01915 (CV098_01915) yabA 382066..382392 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  CV098_RS01920 (CV098_01920) rsmI 382392..383267 (+) 876 WP_010905318.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  CV098_RS01925 (CV098_01925) - 383344..383535 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54649.12 Da        Isoelectric Point: 4.5889

>NTDB_id=215689 CV098_RS01890 WP_012897229.1 377297..378739(-) (vicK) [Lactococcus lactis subsp. lactis strain G423]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=215689 CV098_RS01890 WP_012897229.1 377297..378739(-) (vicK) [Lactococcus lactis subsp. lactis strain G423]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATT
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCGTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTTATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAAATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGAACAGGTTTAGGCCTCTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAGGGAACGACCTTTA
GTTTTACTCTTCCATATTCTTTAGAAGCTGCAGATGACTGGGATGATGGTACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442