Detailed information NTG0021567

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPR_RS09105
• Genome accession: NC_003098
• Coordinates: 1783327..1784337 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae R6
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1778327..1789337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPR_RS09075 (spr1808)	-	1778347..1779561 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
SPR_RS09080 (spr1809)	-	1779717..1780010 (-)	294	WP_000977365.1	hypothetical protein	-
SPR_RS09085 (spr1810)	-	1780172..1780624 (+)	453	WP_000079154.1	universal stress protein	-
SPR_RS09090 (spr1811)	-	1780659..1782047 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
SPR_RS09095 (spr1812)	-	1782113..1783075 (+)	963	WP_001124777.1	asparaginase	-
SPR_RS09100 (spr1812a)	-	1783072..1783263 (-)	192	WP_001092029.1	hypothetical protein	-
SPR_RS09105 (spr1813)	ccpA	1783327..1784337 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
SPR_RS09110 (spr1814)	-	1784762..1785361 (-)	600	WP_000866719.1	response regulator transcription factor	-
SPR_RS09115 (spr1815)	-	1785363..1786460 (-)	1098	WP_000893546.1	sensor histidine kinase	-
SPR_RS09120 (spr1816)	-	1786460..1787197 (-)	738	WP_000832834.1	ABC transporter permease	-
SPR_RS09125 (spr1817)	-	1787199..1788083 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
SPR_RS09130	-	1788070..1788264 (-)	195	WP_000820180.1	hypothetical protein	-
SPR_RS09135 (spr1818)	-	1788261..1788467 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=21567 SPR_RS09105 WP_000990607.1 1783327..1784337(-) (ccpA) [Streptococcus pneumoniae R6]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=21567 SPR_RS09105 WP_000990607.1 1783327..1784337(-) (ccpA) [Streptococcus pneumoniae R6]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568