Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CV725_RS01860 Genome accession   NZ_CP024951
Coordinates   355608..357584 (+) Length   658 a.a.
NCBI ID   WP_001127908.1    Uniprot ID   -
Organism   Helicobacter pylori B128     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 350608..362584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV725_RS08275 (CV725_01835) - 351339..351539 (-) 201 WP_080006190.1 hypothetical protein -
  CV725_RS01845 (CV725_01840) - 351508..354351 (+) 2844 Protein_347 DUF3519 domain-containing protein -
  CV725_RS01850 (CV725_01845) - 354355..354787 (+) 433 Protein_348 hypothetical protein -
  CV725_RS01855 (CV725_01850) - 354784..355557 (+) 774 WP_000611626.1 hypothetical protein -
  CV725_RS01860 (CV725_01855) uvrB 355608..357584 (+) 1977 WP_001127908.1 excinuclease ABC subunit UvrB Machinery gene
  CV725_RS01865 (CV725_01860) - 357595..358428 (-) 834 WP_000816695.1 outer membrane protein -
  CV725_RS01870 (CV725_01865) purB 358497..359819 (-) 1323 WP_000893823.1 adenylosuccinate lyase -
  CV725_RS01875 (CV725_01870) - 359929..360873 (-) 945 WP_000589022.1 thiamine pyrophosphate-dependent enzyme -
  CV725_RS01880 (CV725_01875) - 360886..362109 (-) 1224 WP_000124345.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  CV725_RS01885 (CV725_01880) - 362119..362511 (-) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 76002.47 Da        Isoelectric Point: 6.7308

>NTDB_id=215459 CV725_RS01860 WP_001127908.1 355608..357584(+) (uvrB) [Helicobacter pylori B128]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKIHNITPKTVTRALEEELKLRDDEIRIAKALKKDKMPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=215459 CV725_RS01860 WP_001127908.1 355608..357584(+) (uvrB) [Helicobacter pylori B128]
ATGCCTTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGAAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCACTTTGATCATGAGCCATAATAAGACCTTATGCGCGCAACTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGGAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGACCACCTCGCTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGTGAGAAGCGCGCTTACAAGAGCTTTTTACTCAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGTGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGCGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCACGCCATTTCACCGGTAAAGCCCCTAACGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAATTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGATAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAATTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCCAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAACCACATCATCCGCTCTTTAAGGCTTAAGGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAGATCACT
CAAAGCATGCAAAAAGCCTTTGAGATAACGAGTTACAGGCGCGCTAAGCAAGAAGAGTTCAATAAAATCCATAACATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAATTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCCTTAAAAA
AGGACAAAATGCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAATTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

UvrB interaction domain (UvrB_inter)

(159-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.623

100

0.5
  uvrB Streptococcus pneumoniae TIGR4

49.623

100

0.5
  uvrB Streptococcus pneumoniae D39

49.623

100

0.5