Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CV728_RS01875 Genome accession   NZ_CP024948
Coordinates   355138..357114 (+) Length   658 a.a.
NCBI ID   WP_145816728.1    Uniprot ID   -
Organism   Helicobacter pylori strain B140     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 350138..362114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV728_RS01855 (CV728_01855) - 350216..350986 (+) 771 WP_145816721.1 HP1117 family Sel1-like repeat protein -
  CV728_RS01860 (CV728_01860) - 351199..351429 (-) 231 WP_145816722.1 hypothetical protein -
  CV728_RS01865 (CV728_01865) - 351767..354280 (+) 2514 WP_194151475.1 DUF3519 domain-containing protein -
  CV728_RS01870 (CV728_01870) - 354282..355097 (+) 816 WP_145816726.1 hypothetical protein -
  CV728_RS01875 (CV728_01875) uvrB 355138..357114 (+) 1977 WP_145816728.1 excinuclease ABC subunit UvrB Machinery gene
  CV728_RS01880 (CV728_01880) - 357125..357958 (-) 834 WP_145816730.1 outer membrane protein -
  CV728_RS01885 (CV728_01885) purB 358023..359345 (-) 1323 WP_145816732.1 adenylosuccinate lyase -
  CV728_RS01890 (CV728_01890) - 359455..360399 (-) 945 WP_145816734.1 thiamine pyrophosphate-dependent enzyme -
  CV728_RS01895 (CV728_01895) - 360412..361635 (-) 1224 WP_145816736.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  CV728_RS01900 (CV728_01900) - 361645..362037 (-) 393 WP_000656172.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75988.54 Da        Isoelectric Point: 6.8805

>NTDB_id=215337 CV728_RS01875 WP_145816728.1 355138..357114(+) (uvrB) [Helicobacter pylori strain B140]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANVIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRAMGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKIHNITPKTVTRALEEELKLRDDEIRIAKALKKDKMPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=215337 CV728_RS01875 WP_145816728.1 355138..357114(+) (uvrB) [Helicobacter pylori strain B140]
ATGCCTTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCTTTAACAAAAAGCTT
GAAAAATAACAACCATTATCAAACTCTAGTGGGGGTTACAGGGAGCGGTAAGACTTACACAATGGCTAATGTCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTCTATAGCGAATTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAGAGCTATATCCCTAGAAGGGATTTGTT
CATTGAAAAAGACAGCTCTATTAACGATGATTTGGAGCGTTTGAGATTGAGCGCGACCACTTCGCTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTGAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGTGCTTACAAGAGCTTTTTATTAAAGCTAGTGGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGATGGGGGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAACTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGGTTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACGGGTAAAGCCCCCAATGAAACG
CCCTTTTGTTTGTTTGATTATTTAGGGATTTTTGAGCGGGAGTTTTTAGTCATTGTAGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAATTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTCGAATTAGAGCTTTCCAAAAAGAATGTTGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGCTAGTGGTGGCTAGAGATGAAAGGGTGTTAATTA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAGATCACT
CAAAGCATGCAAAAAGCCTTTGAGATCACTAGTTACAGGCGCGCCAAGCAAGAAGAGTTCAATAAAATCCATAACATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAATTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCCTTAAAAA
AGGACAAAATGCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAATTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCAAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB/uvrC motif (UVR)

(623-657)

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB interaction domain (UvrB_inter)

(159-248)

Type III restriction enzyme, res subunit (ResIII)

(15-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.623

100

0.5
  uvrB Streptococcus pneumoniae TIGR4

49.623

100

0.5
  uvrB Streptococcus pneumoniae D39

49.623

100

0.5