Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CV729_RS06465 Genome accession   NZ_CP024947
Coordinates   1326140..1328116 (-) Length   658 a.a.
NCBI ID   WP_120909088.1    Uniprot ID   -
Organism   Helicobacter pylori strain J182     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1321140..1333116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV729_RS06440 (CV729_06445) - 1321216..1321608 (+) 393 WP_000656173.1 4Fe-4S dicluster domain-containing protein -
  CV729_RS06445 (CV729_06450) - 1321618..1322841 (+) 1224 WP_000124331.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  CV729_RS06450 (CV729_06455) - 1322854..1323798 (+) 945 WP_145733143.1 thiamine pyrophosphate-dependent enzyme -
  CV729_RS06455 (CV729_06460) purB 1323908..1325230 (+) 1323 WP_145733145.1 adenylosuccinate lyase -
  CV729_RS06460 (CV729_06465) - 1325296..1326129 (+) 834 WP_145733147.1 outer membrane protein -
  CV729_RS06465 (CV729_06470) uvrB 1326140..1328116 (-) 1977 WP_120909088.1 excinuclease ABC subunit UvrB Machinery gene
  CV729_RS06470 (CV729_06475) - 1328186..1329103 (-) 918 WP_145733148.1 hypothetical protein -
  CV729_RS06475 (CV729_06480) - 1329164..1331915 (-) 2752 Protein_1229 DUF3519 domain-containing protein -
  CV729_RS08245 - 1331884..1332084 (+) 201 Protein_1230 hypothetical protein -
  CV729_RS08520 (CV729_06485) - 1332081..1332337 (+) 257 Protein_1231 hypothetical protein -
  CV729_RS06485 (CV729_06490) - 1332326..1333096 (-) 771 WP_145733152.1 HP1117 family Sel1-like repeat protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75972.44 Da        Isoelectric Point: 6.7308

>NTDB_id=215328 CV729_RS06465 WP_120909088.1 1326140..1328116(-) (uvrB) [Helicobacter pylori strain J182]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKIHNITPKTVTRALEEELKLRDDEIRIAKALKKDKMPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=215328 CV729_RS06465 WP_120909088.1 1326140..1328116(-) (uvrB) [Helicobacter pylori strain J182]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACAAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGAAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGTGCAACCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTGAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGGGCGACGGGGGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCTGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TCTAAGGTTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAACGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATTTTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTGTTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAACCACATCATCCGCTCTTTAAGGCTTAAGGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAGATCACT
CAAAGCATGCAAAAAGCCTTTGAGATAACGAGTTACAGGCGCGCTAAGCAAGAAGAGTTCAATAAAATCCATAACATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAATTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCCTTAAAAA
AGGACAAGATGCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAATTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB/uvrC motif (UVR)

(623-657)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498

Multiple sequence alignment