Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AM346_RS17730 Genome accession   NZ_CP024889
Coordinates   3350968..3351600 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AR_0019     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3345968..3356600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM346_RS17700 (AM346_17670) yheS 3346137..3348050 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  AM346_RS17705 (AM346_17675) yheT 3348050..3349072 (+) 1023 WP_000057410.1 hydrolase -
  AM346_RS17710 (AM346_17680) yheU 3349066..3349284 (+) 219 WP_000907085.1 YheU family protein -
  AM346_RS17715 (AM346_17685) prkB 3349338..3350207 (+) 870 WP_001274683.1 phosphoribulokinase -
  AM346_RS17720 (AM346_17690) yhfA 3350262..3350666 (-) 405 WP_001148908.1 OsmC family protein -
  AM346_RS17730 (AM346_17700) crp 3350968..3351600 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AM346_RS17735 (AM346_17705) yhfK 3351651..3353741 (+) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  AM346_RS17740 (AM346_17710) argD 3353808..3355028 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AM346_RS17745 (AM346_17715) pabA 3355114..3355677 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AM346_RS17750 (AM346_17720) fic 3355709..3356311 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AM346_RS17755 (AM346_17725) yhfG 3356301..3356468 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=215232 AM346_RS17730 WP_000242755.1 3350968..3351600(+) (crp) [Escherichia coli strain AR_0019]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=215232 AM346_RS17730 WP_000242755.1 3350968..3351600(+) (crp) [Escherichia coli strain AR_0019]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467