Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AM342_RS10270 Genome accession   NZ_CP024862
Coordinates   1990191..1990823 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AR_0015     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1985191..1995823
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM342_RS10240 (AM342_10230) yheS 1985360..1987273 (+) 1914 WP_020232893.1 ABC transporter ATP-binding protein -
  AM342_RS10245 (AM342_10235) yheT 1987273..1988295 (+) 1023 WP_001521449.1 hydrolase -
  AM342_RS10250 (AM342_10240) yheU 1988289..1988507 (+) 219 WP_000907085.1 YheU family protein -
  AM342_RS10255 (AM342_10245) prkB 1988561..1989430 (+) 870 WP_001274680.1 phosphoribulokinase -
  AM342_RS10260 (AM342_10250) yhfA 1989485..1989889 (-) 405 WP_001148908.1 OsmC family protein -
  AM342_RS10270 (AM342_10260) crp 1990191..1990823 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AM342_RS10275 (AM342_10265) yhfK 1990874..1992964 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AM342_RS10280 (AM342_10270) argD 1993031..1994251 (-) 1221 WP_000963771.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AM342_RS10285 (AM342_10275) pabA 1994337..1994900 (-) 564 WP_001521451.1 aminodeoxychorismate synthase component 2 -
  AM342_RS10290 (AM342_10280) fic 1994932..1995534 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  AM342_RS10295 (AM342_10285) yhfG 1995524..1995691 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=214952 AM342_RS10270 WP_000242755.1 1990191..1990823(+) (crp) [Escherichia coli strain AR_0015]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=214952 AM342_RS10270 WP_000242755.1 1990191..1990823(+) (crp) [Escherichia coli strain AR_0015]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGCCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATAGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment