Detailed information NTG0021490

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SP_RS10050
• Genome accession: NC_003028
• Coordinates: 1902314..1903324 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae TIGR4
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1897314..1908324

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP_RS10025 (SP_1995)	-	1898299..1898593 (-)	295	Protein_1892	hypothetical protein	-
SP_RS10030 (SP_1996)	-	1898755..1899207 (+)	453	WP_000079148.1	universal stress protein	-
SP_RS10035 (SP_1997)	-	1899242..1900630 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
SP_RS10040 (SP_1998)	-	1900696..1901658 (+)	963	WP_001124777.1	asparaginase	-
SP_RS10045	-	1901687..1902250 (-)	564	WP_001092024.1	hypothetical protein	-
SP_RS10050 (SP_1999)	ccpA	1902314..1903324 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
SP_RS10055 (SP_2000)	-	1903749..1904348 (-)	600	WP_000866703.1	response regulator transcription factor	-
SP_RS10060 (SP_2001)	-	1904349..1905446 (-)	1098	WP_000893503.1	sensor histidine kinase	-
SP_RS10065 (SP_2002)	-	1905446..1906183 (-)	738	WP_000832915.1	ABC transporter permease	-
SP_RS10070 (SP_2003)	-	1906185..1907069 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
SP_RS10075 (SP_2004)	-	1907056..1907250 (-)	195	WP_000820189.1	hypothetical protein	-
SP_RS13520	-	1907247..1907453 (-)	207	Protein_1903	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=21490 SP_RS10050 WP_000990607.1 1902314..1903324(-) (ccpA) [Streptococcus pneumoniae TIGR4]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=21490 SP_RS10050 WP_000990607.1 1902314..1903324(-) (ccpA) [Streptococcus pneumoniae TIGR4]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568