Detailed information NTG0214721

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: BWQ98_RS09905
• Genome accession: NZ_CP019299
• Coordinates: 1825584..1826045 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain HKU1-14
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1820584..1831045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWQ98_RS09875 (BWQ98_09895)	-	1820888..1821712 (-)	825	WP_201417385.1	membrane protein insertase YidC	-
BWQ98_RS09880 (BWQ98_09900)	rnpA	1821687..1822058 (-)	372	WP_000739246.1	ribonuclease P protein component	-
BWQ98_RS11740	-	1822075..1822206 (-)	132	WP_000768904.1	hypothetical protein	-
BWQ98_RS09885 (BWQ98_09905)	-	1822207..1823397 (-)	1191	WP_050233485.1	acetate kinase	-
BWQ98_RS09890 (BWQ98_09910)	comYH	1823448..1824401 (-)	954	WP_050233486.1	class I SAM-dependent methyltransferase	Machinery gene
BWQ98_RS09895 (BWQ98_09915)	-	1824462..1825056 (-)	595	Protein_1841	methyltransferase domain-containing protein	-
BWQ98_RS09900 (BWQ98_09920)	comGG/cglG	1825193..1825606 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
BWQ98_RS09905 (BWQ98_09925)	comGF/cglF	1825584..1826045 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
BWQ98_RS09910 (BWQ98_09930)	comGE/cglE	1826008..1826310 (-)	303	WP_226372546.1	competence type IV pilus minor pilin ComGE	Machinery gene
BWQ98_RS09915 (BWQ98_09935)	comGD/cglD	1826273..1826677 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
BWQ98_RS09920 (BWQ98_09940)	comGC/cglC	1826670..1826996 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
BWQ98_RS09925 (BWQ98_09945)	comGB/cglB	1826998..1828014 (-)	1017	WP_078134945.1	competence type IV pilus assembly protein ComGB	Machinery gene
BWQ98_RS09930 (BWQ98_09950)	comGA/cglA/cilD	1827962..1828903 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
BWQ98_RS09935 (BWQ98_09955)	-	1828979..1829344 (-)	366	WP_050212688.1	DUF1033 family protein	-
BWQ98_RS09940 (BWQ98_09960)	-	1829495..1830553 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=214721 BWQ98_RS09905 WP_000250542.1 1825584..1826045(-) (comGF/cglF) [Streptococcus pneumoniae strain HKU1-14]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=214721 BWQ98_RS09905 WP_000250542.1 1825584..1826045(-) (comGF/cglF) [Streptococcus pneumoniae strain HKU1-14]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909