Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CU076_RS00975 Genome accession   NZ_CP024830
Coordinates   177033..177692 (+) Length   219 a.a.
NCBI ID   WP_100183821.1    Uniprot ID   -
Organism   Escherichia coli strain CREC-532     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 172033..182692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CU076_RS00950 (CU076_00950) ygiS 173316..174923 (-) 1608 WP_001295629.1 ABC transporter substrate-binding protein -
  CU076_RS00955 (CU076_00955) mqsA 175056..175451 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  CU076_RS00960 (CU076_00960) mqsR 175453..175749 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  CU076_RS00965 (CU076_00965) ygiV 175954..176436 (-) 483 WP_000183505.1 GyrI-like domain-containing protein -
  CU076_RS00970 (CU076_00970) ygiW 176489..176881 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  CU076_RS00975 (CU076_00975) ciaR 177033..177692 (+) 660 WP_100183821.1 quorum sensing response regulator transcription factor QseB Regulator
  CU076_RS00980 (CU076_00980) qseC 177689..179038 (+) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  CU076_RS00985 (CU076_00985) ygiZ 179084..179416 (-) 333 WP_000917685.1 DUF2645 family protein -
  CU076_RS00995 (CU076_00995) mdaB 179735..180316 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CU076_RS01000 (CU076_01000) ygiN 180347..180661 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  CU076_RS01005 (CU076_01005) parE 180709..182601 (-) 1893 WP_000195292.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24729.71 Da        Isoelectric Point: 6.9850

>NTDB_id=214593 CU076_RS00975 WP_100183821.1 177033..177692(+) (ciaR) [Escherichia coli strain CREC-532]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDVLAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTLHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=214593 CU076_RS00975 WP_100183821.1 177033..177692(+) (ciaR) [Escherichia coli strain CREC-532]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGTGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCTTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.767

100

0.402
  ciaR Streptococcus pneumoniae D39

38.767

100

0.402
  ciaR Streptococcus pneumoniae R6

38.767

100

0.402
  ciaR Streptococcus pneumoniae TIGR4

38.767

100

0.402
  ciaR Streptococcus mutans UA159

36.323

100

0.37