Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CU078_RS18115 Genome accession   NZ_CP024821
Coordinates   3445970..3446602 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CREC-591     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3440970..3451602
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CU078_RS18090 (CU078_18090) yhfG 3441102..3441269 (+) 168 WP_000736860.1 YhfG family protein -
  CU078_RS18095 (CU078_18095) fic 3441259..3441861 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CU078_RS18100 (CU078_18100) pabA 3441893..3442456 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CU078_RS18105 (CU078_18105) argD 3442542..3443762 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CU078_RS18110 (CU078_18110) yhfK 3443829..3445919 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CU078_RS18115 (CU078_18115) crp 3445970..3446602 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CU078_RS18125 (CU078_18125) yhfA 3446904..3447308 (+) 405 WP_001148908.1 OsmC family protein -
  CU078_RS18130 (CU078_18130) prkB 3447363..3448232 (-) 870 WP_001274680.1 phosphoribulokinase -
  CU078_RS18135 (CU078_18135) yheU 3448286..3448504 (-) 219 WP_000907085.1 YheU family protein -
  CU078_RS18140 (CU078_18140) yheT 3448498..3449520 (-) 1023 WP_000057379.1 hydrolase -
  CU078_RS18145 (CU078_18145) yheS 3449520..3451433 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=214476 CU078_RS18115 WP_000242755.1 3445970..3446602(-) (crp) [Escherichia coli strain CREC-591]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=214476 CU078_RS18115 WP_000242755.1 3445970..3446602(-) (crp) [Escherichia coli strain CREC-591]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467