Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CDW44_RS19020 Genome accession   NZ_CP024650
Coordinates   3724763..3725395 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain BH100 substr. MG2014     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3719763..3730395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CDW44_RS18990 (CDW44_19315) yheS 3719932..3721845 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CDW44_RS18995 (CDW44_19320) yheT 3721845..3722867 (+) 1023 WP_000057389.1 hydrolase -
  CDW44_RS19000 (CDW44_19325) yheU 3722861..3723079 (+) 219 WP_000907085.1 YheU family protein -
  CDW44_RS19005 (CDW44_19330) prkB 3723133..3724002 (+) 870 WP_001274680.1 phosphoribulokinase -
  CDW44_RS19010 (CDW44_19335) yhfA 3724057..3724461 (-) 405 WP_001148908.1 OsmC family protein -
  CDW44_RS19020 (CDW44_19345) crp 3724763..3725395 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CDW44_RS19025 (CDW44_19350) yhfK 3725446..3727536 (+) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  CDW44_RS19030 (CDW44_19355) argD 3727614..3728834 (-) 1221 WP_000963809.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CDW44_RS19035 (CDW44_19360) pabA 3728920..3729483 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  CDW44_RS19040 (CDW44_19365) fic 3729515..3730117 (-) 603 WP_001280615.1 putative adenosine monophosphate-protein transferase Fic -
  CDW44_RS19045 (CDW44_19370) yhfG 3730107..3730274 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=213973 CDW44_RS19020 WP_000242755.1 3724763..3725395(+) (crp) [Escherichia coli strain BH100 substr. MG2014]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=213973 CDW44_RS19020 WP_000242755.1 3724763..3725395(+) (crp) [Escherichia coli strain BH100 substr. MG2014]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467