Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A5960_RS22555 Genome accession   NZ_CP024289
Coordinates   4352784..4353416 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O178:H19 strain 2012C-4431     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4347784..4358416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5960_RS22530 yhfG 4347916..4348083 (+) 168 WP_000736860.1 YhfG family protein -
  A5960_RS22535 fic 4348073..4348675 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  A5960_RS22540 pabA 4348707..4349270 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  A5960_RS22545 argD 4349356..4350576 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A5960_RS22550 yhfK 4350643..4352733 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  A5960_RS22555 crp 4352784..4353416 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A5960_RS22565 yhfA 4353718..4354122 (+) 405 WP_001148908.1 OsmC family protein -
  A5960_RS22570 prkB 4354177..4355046 (-) 870 WP_001274680.1 phosphoribulokinase -
  A5960_RS22575 yheU 4355100..4355318 (-) 219 WP_000907085.1 YheU family protein -
  A5960_RS22580 yheT 4355312..4356334 (-) 1023 WP_000057405.1 hydrolase -
  A5960_RS22585 yheS 4356334..4358247 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=212712 A5960_RS22555 WP_000242755.1 4352784..4353416(-) (crp) [Escherichia coli O178:H19 strain 2012C-4431]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=212712 A5960_RS22555 WP_000242755.1 4352784..4353416(-) (crp) [Escherichia coli O178:H19 strain 2012C-4431]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment