Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   COG38_RS15565 Genome accession   NZ_CP024263
Coordinates   2992843..2993475 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O169:H41 strain F6326-C1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2987843..2998475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COG38_RS15535 yheS 2988012..2989925 (+) 1914 WP_001613950.1 ABC transporter ATP-binding protein -
  COG38_RS15540 yheT 2989925..2990947 (+) 1023 WP_000057392.1 hydrolase -
  COG38_RS15545 yheU 2990941..2991159 (+) 219 WP_000907085.1 YheU family protein -
  COG38_RS15550 prkB 2991213..2992082 (+) 870 WP_001274680.1 phosphoribulokinase -
  COG38_RS15555 yhfA 2992137..2992541 (-) 405 WP_001148908.1 OsmC family protein -
  COG38_RS15565 crp 2992843..2993475 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  COG38_RS15570 yhfK 2993526..2995616 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  COG38_RS15575 argD 2995683..2996903 (-) 1221 WP_001718947.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  COG38_RS15580 pabA 2996989..2997552 (-) 564 WP_001718948.1 aminodeoxychorismate synthase component 2 -
  COG38_RS15585 fic 2997584..2998186 (-) 603 WP_001718949.1 putative adenosine monophosphate-protein transferase Fic -
  COG38_RS15590 yhfG 2998176..2998343 (-) 168 WP_032201336.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=212285 COG38_RS15565 WP_000242755.1 2992843..2993475(+) (crp) [Escherichia coli O169:H41 strain F6326-C1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=212285 COG38_RS15565 WP_000242755.1 2992843..2993475(+) (crp) [Escherichia coli O169:H41 strain F6326-C1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467