Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   COG34_RS13380 Genome accession   NZ_CP024243
Coordinates   2606671..2607303 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O128:H27 strain 90-9281     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2601671..2612303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COG34_RS13355 yhfG 2601803..2601970 (+) 168 WP_000736862.1 YhfG family protein -
  COG34_RS13360 fic 2601960..2602562 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  COG34_RS13365 pabA 2602594..2603157 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  COG34_RS13370 argD 2603243..2604463 (+) 1221 WP_000963784.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  COG34_RS13375 yhfK 2604530..2606620 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  COG34_RS13380 crp 2606671..2607303 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  COG34_RS13390 yhfA 2607605..2608009 (+) 405 WP_001148908.1 OsmC family protein -
  COG34_RS13395 prkB 2608064..2608933 (-) 870 WP_001274680.1 phosphoribulokinase -
  COG34_RS13400 yheU 2608987..2609205 (-) 219 WP_000907085.1 YheU family protein -
  COG34_RS13405 yheT 2609199..2610221 (-) 1023 WP_000057405.1 hydrolase -
  COG34_RS13410 yheS 2610221..2612134 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=211876 COG34_RS13380 WP_000242755.1 2606671..2607303(-) (crp) [Escherichia coli O128:H27 strain 90-9281]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=211876 COG34_RS13380 WP_000242755.1 2606671..2607303(-) (crp) [Escherichia coli O128:H27 strain 90-9281]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment