Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   COG33_RS14315 Genome accession   NZ_CP024240
Coordinates   2665717..2666349 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O114:H49 strain 90-9280     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2660717..2671349
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COG33_RS14285 yheS 2660886..2662799 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  COG33_RS14290 yheT 2662799..2663821 (+) 1023 WP_000057405.1 hydrolase -
  COG33_RS14295 yheU 2663815..2664033 (+) 219 WP_000907085.1 YheU family protein -
  COG33_RS14300 prkB 2664087..2664956 (+) 870 WP_001274680.1 phosphoribulokinase -
  COG33_RS14305 yhfA 2665011..2665415 (-) 405 WP_001148908.1 OsmC family protein -
  COG33_RS14315 crp 2665717..2666349 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  COG33_RS14320 yhfK 2666400..2668490 (+) 2091 WP_001356072.1 YccS/YhfK family putative transporter -
  COG33_RS14325 argD 2668557..2669777 (-) 1221 WP_000963766.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  COG33_RS14330 pabA 2669863..2670426 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  COG33_RS14335 fic 2670458..2671060 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  COG33_RS14340 yhfG 2671050..2671217 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=211790 COG33_RS14315 WP_000242755.1 2665717..2666349(+) (crp) [Escherichia coli O114:H49 strain 90-9280]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=211790 COG33_RS14315 WP_000242755.1 2665717..2666349(+) (crp) [Escherichia coli O114:H49 strain 90-9280]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467