Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilE   Type   Machinery gene
Locus tag   NGO_RS10430 Genome accession   NC_002946
Coordinates   2038837..2039259 (-) Length   140 a.a.
NCBI ID   WP_157147417.1    Uniprot ID   A0A0H4IWJ4
Organism   Neisseria gonorrhoeae FA 1090     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2033837..2044259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NGO_RS10415 (NGO2060) pilA 2034823..2036088 (+) 1266 WP_010951395.1 signal recognition particle-docking protein FtsY Machinery gene
  NGO_RS10420 (NGO2060a) - 2036384..2037186 (-) 803 Protein_2046 opacity family porin -
  NGO_RS11975 - 2037522..2038021 (-) 500 Protein_2047 pilin -
  NGO_RS11185 - 2038639..2038719 (-) 81 Protein_2048 pilin -
  NGO_RS10430 (NGO_11115) pilE 2038837..2039259 (-) 423 WP_157147417.1 pilin Machinery gene
  NGO_RS10435 (NGO2065) lpxC 2039365..2040288 (-) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  NGO_RS10440 (NGO_11125) - 2040862..2041203 (-) 342 Protein_2051 pilin -
  NGO_RS11980 - 2041256..2041606 (-) 351 Protein_2052 pilin -
  NGO_RS11985 - 2041646..2042026 (-) 381 Protein_2053 pilin -
  NGO_RS11190 - 2042470..2042762 (-) 293 Protein_2054 pilin -
  NGO_RS10455 - 2042783..2043139 (-) 357 Protein_2055 pilin -
  NGO_RS10460 (NGO_11140) pilE 2043130..2043561 (-) 432 WP_157147418.1 pilin Machinery gene

Sequence


Protein


Download         Length: 140 a.a.        Molecular weight: 14769.36 Da        Isoelectric Point: 6.4594

>NTDB_id=21176 NGO_RS10430 WP_157147417.1 2038837..2039259(-) (pilE) [Neisseria gonorrhoeae FA 1090]
MPTDPDSRLRGNDEAILLAEGQKSAVAGYCPNHGKWPANNGDAGVASSAEIKGKYVKSVTVANGVVTAEMASSGVNKEIK
GKRLSLWARRQDGSVKWFCGQPVTRNDAADNDDVAKDDAAGNAIETKHLPSTCRDEPTAT

Nucleotide


Download         Length: 423 bp        

>NTDB_id=21176 NGO_RS10430 WP_157147417.1 2038837..2039259(-) (pilE) [Neisseria gonorrhoeae FA 1090]
GTGCCGACAGACCCGGATTCCCGCCTGCGCGGGAATGACGAAGCCATCCTTTTGGCCGAAGGCCAAAAATCAGCCGTTGC
CGGGTATTGCCCGAATCACGGCAAATGGCCCGCAAACAACGGTGATGCCGGCGTGGCATCCTCCGCCGAAATCAAAGGCA
AATATGTTAAAAGCGTTACGGTCGCAAACGGCGTCGTTACCGCCGAAATGGCTTCAAGCGGCGTAAACAAAGAAATCAAA
GGCAAAAGACTCTCCCTGTGGGCCAGGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTACGCGCAACGA
CGCCGCCGACAACGACGACGTCGCCAAAGACGACGCCGCCGGCAACGCCATCGAAACCAAGCACCTGCCGTCAACCTGCC
GCGATGAACCAACTGCCACCTAA

Domains


Predicted by InterproScan.

(14-134)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H4IWJ4

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae strain FA1090

67.376

100

0.679

  pilE Neisseria gonorrhoeae MS11

65.942

98.571

0.65


Multiple sequence alignment