Detailed information NTG0021175

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NGO_RS10415
• Genome accession: NC_002946
• Coordinates: 2034823..2036088 (+)
• Length: 421 a.a.
• NCBI ID: WP_010951395.1
• Uniprot ID: Q5F570
• Organism: Neisseria gonorrhoeae FA 1090
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2029823..2041088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NGO_RS10395 (NGO2056)	-	2030574..2031575 (+)	1002	WP_003686999.1	thiamine ABC transporter substrate-binding protein	-
NGO_RS10400 (NGO2057)	-	2031669..2032517 (+)	849	WP_003687000.1	mechanosensitive ion channel family protein	-
NGO_RS10405 (NGO2058)	-	2032543..2033025 (+)	483	WP_003694396.1	CinA family protein	-
NGO_RS10410 (NGO2059)	msrAB	2033109..2034677 (-)	1569	WP_010951394.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
NGO_RS10415 (NGO2060)	pilA	2034823..2036088 (+)	1266	WP_010951395.1	signal recognition particle-docking protein FtsY	Machinery gene
NGO_RS10420 (NGO2060a)	-	2036384..2037186 (-)	803	Protein_2046	opacity family porin	-
NGO_RS11975	-	2037522..2038021 (-)	500	Protein_2047	pilin	-
NGO_RS11185	-	2038639..2038719 (-)	81	Protein_2048	pilin	-
NGO_RS10430 (NGO_11115)	pilE	2038837..2039259 (-)	423	WP_157147417.1	pilin	Machinery gene
NGO_RS10435 (NGO2065)	lpxC	2039365..2040288 (-)	924	WP_003687007.1	UDP-3-O-acyl-N-acetylglucosamine deacetylase	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 44759.20 Da
• Isoelectric Point: 4.8737

>NTDB_id=21175 NGO_RS10415 WP_010951395.1 2034823..2036088(+) (pilA) [Neisseria gonorrhoeae FA 1090]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAEKAVERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELET
VLITGDMGMEATEYLMKDVRGRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=21175 NGO_RS10415 WP_010951395.1 2034823..2036088(+) (pilA) [Neisseria gonorrhoeae FA 1090]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCTGAAAAAGCGGTGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCAC
GCGACAAAATGGCGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCGGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGGCCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGG
TCTTGCCCGAAACTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCA
GCTTCAGGCTTGGGGCGGGCGCAACAATGTAACCGTCATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGA
TGCCAATATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAGGCATAGACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: Q5F570

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	99.05	100	0.991