Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CNZ63_RS13120 Genome accession   NZ_CP024232
Coordinates   2547385..2548017 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O6:H16 strain 2014EL-1346-6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2542385..2553017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CNZ63_RS13095 yhfG 2542517..2542684 (+) 168 WP_000736860.1 YhfG family protein -
  CNZ63_RS13100 fic 2542674..2543276 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CNZ63_RS13105 pabA 2543308..2543871 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CNZ63_RS13110 argD 2543957..2545177 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CNZ63_RS13115 yhfK 2545244..2547334 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CNZ63_RS13120 crp 2547385..2548017 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CNZ63_RS13130 yhfA 2548319..2548723 (+) 405 WP_001148908.1 OsmC family protein -
  CNZ63_RS13135 prkB 2548778..2549647 (-) 870 WP_001274680.1 phosphoribulokinase -
  CNZ63_RS13140 yheU 2549701..2549919 (-) 219 WP_000907085.1 YheU family protein -
  CNZ63_RS13145 yheT 2549913..2550935 (-) 1023 WP_000057356.1 hydrolase -
  CNZ63_RS13150 yheS 2550935..2552848 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=211714 CNZ63_RS13120 WP_000242755.1 2547385..2548017(-) (crp) [Escherichia coli O6:H16 strain 2014EL-1346-6]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=211714 CNZ63_RS13120 WP_000242755.1 2547385..2548017(-) (crp) [Escherichia coli O6:H16 strain 2014EL-1346-6]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment