Detailed information NTG0211322

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: BLE401_RS04940
• Genome accession: NZ_CP018889
• Coordinates: 1186948..1188318 (+)
• Length: 456 a.a.
• NCBI ID: WP_062149860.1
• Uniprot ID: A0A2N9YAE6
• Organism: Beggiatoa leptomitoformis strain D-401
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1181948..1193318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BLE401_RS04925 (BLE401_01085)	-	1182271..1184433 (+)	2163	WP_062149850.1	chemotaxis protein CheA	-
BLE401_RS04930 (BLE401_01080)	-	1184430..1184918 (+)	489	WP_062149853.1	chemotaxis protein CheW	-
BLE401_RS04935 (BLE401_01075)	-	1185258..1186883 (+)	1626	WP_062149856.1	sensor histidine kinase	-
BLE401_RS04940 (BLE401_01070)	pilR	1186948..1188318 (+)	1371	WP_062149860.1	sigma-54-dependent transcriptional regulator	Regulator
BLE401_RS04945 (BLE401_01065)	-	1188587..1189849 (+)	1263	WP_062149863.1	tetratricopeptide repeat protein	-
BLE401_RS04950 (BLE401_01060)	-	1189904..1190254 (-)	351	WP_062149865.1	slr1659 superfamily regulator	-
BLE401_RS04955 (BLE401_01055)	-	1190450..1192798 (+)	2349	WP_161575430.1	PAS domain S-box protein	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 50430.03 Da
• Isoelectric Point: 5.2550

>NTDB_id=211322 BLE401_RS04940 WP_062149860.1 1186948..1188318(+) (pilR) [Beggiatoa leptomitoformis strain D-401]
MSCPKCLVVDDEPIILELSAQTLSSMNIDCVGAGSFAEACEYLKTQMFDLCLTDMHLPDGNGIDLVTLIQQEYSNTPVAM
ITAFGSVESAVQALKAGAFDFVTKPVDIKALRVLVSTALKLSEKHEDSFSSLVGESCAIQSLRVKIAKLARSQAPVYIRG
ESGVGKEVVARLIHTQGARASKSFVPVNCGAIPTELMESEFFGHKKGSFTGANTDKPGLFQTAQGGTLFLDEVADLPLHM
QVKLLRVIQEKQMRPVGAAKEISVDVRILSATHRDLADLVKQGKFRQDLFYRINVIEINVPPLRERIEDIPLLVERILQK
LTDNGGKTDLRLSSEAMTFLQSYHFPGNVRELENILERAMTLCEGNIIQLDDLQLPTIKDDIEMTEEDYGTWVNVSSTEA
HAEGLDPLLEDVEKERIMKALEKTRGNKTHAAKLLGISFGALRYRLTKFNLRFNSD

Nucleotide

• Length: 1371 bp

>NTDB_id=211322 BLE401_RS04940 WP_062149860.1 1186948..1188318(+) (pilR) [Beggiatoa leptomitoformis strain D-401]
ATGTCATGTCCGAAATGTCTTGTTGTTGACGATGAGCCAATTATTCTTGAACTCTCAGCACAGACGCTAAGCTCTATGAA
TATTGATTGTGTCGGTGCTGGTTCATTTGCTGAAGCATGTGAATATTTAAAAACACAGATGTTTGATTTATGTTTGACAG
ACATGCACTTACCTGATGGTAATGGCATTGATTTGGTAACACTGATTCAGCAAGAATATAGTAATACACCTGTCGCCATG
ATCACTGCTTTTGGTAGTGTAGAATCTGCGGTACAGGCATTAAAAGCAGGCGCGTTTGATTTTGTAACCAAACCTGTGGA
TATTAAAGCCTTGCGGGTTTTAGTCAGTACCGCGCTTAAATTATCAGAAAAACATGAAGATAGTTTTTCTTCTCTCGTTG
GAGAATCTTGCGCGATTCAATCTTTGCGCGTAAAAATTGCCAAACTTGCCCGCAGTCAAGCACCTGTTTATATTCGTGGA
GAATCTGGCGTGGGTAAAGAAGTGGTCGCCCGTTTGATACATACGCAAGGTGCAAGAGCAAGTAAGTCTTTTGTCCCTGT
TAATTGCGGCGCAATTCCAACCGAATTGATGGAAAGCGAGTTTTTCGGGCATAAAAAGGGCAGTTTTACAGGTGCGAACA
CCGATAAACCCGGTTTATTTCAAACAGCACAGGGCGGAACATTGTTTCTTGATGAGGTTGCTGATTTACCGCTGCACATG
CAGGTCAAATTATTGCGTGTTATTCAAGAAAAACAAATGCGTCCTGTGGGTGCGGCGAAAGAAATTTCTGTTGATGTGCG
AATTCTTAGCGCAACCCATCGCGATTTAGCGGATTTAGTTAAGCAAGGCAAATTTCGCCAAGATTTGTTTTATCGGATTA
ATGTAATTGAAATTAATGTTCCACCGTTGCGGGAACGTATAGAAGACATTCCCTTATTAGTTGAGCGGATTTTGCAAAAG
CTCACGGATAATGGGGGAAAAACGGATTTACGTCTATCATCTGAGGCAATGACCTTTTTGCAAAGCTATCATTTTCCGGG
AAATGTCCGTGAATTGGAAAATATTTTAGAGCGTGCCATGACCTTATGCGAAGGTAATATCATTCAACTTGATGATTTAC
AATTACCGACGATAAAAGATGATATCGAAATGACGGAAGAAGATTATGGCACATGGGTAAATGTGTCATCGACAGAAGCC
CACGCCGAAGGACTAGACCCTTTATTAGAAGATGTAGAAAAAGAACGCATTATGAAGGCATTGGAAAAGACCAGAGGGAA
TAAAACCCATGCTGCAAAGTTGTTAGGAATTAGTTTTGGTGCGTTGCGTTATCGCTTAACAAAATTCAATTTGCGGTTCA
ATTCTGACTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-113)

• Bacterial regulatory protein, Fis family (HTH_8) (409-449)

• Sigma-54 interaction domain (Sigma54_activat) (132-298)

3D structure

• AlphaFold DB: A0A2N9YAE6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	59.251	99.561	0.59
pilR	Acinetobacter baumannii strain A118	48.696	100	0.491
luxO	Vibrio cholerae strain A1552	36.703	99.781	0.366