Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CR537_RS02465 Genome accession   NZ_CP024138
Coordinates   490770..491402 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 14EC020     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 485770..496402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR537_RS02440 (CR537_02445) yhfG 485902..486069 (+) 168 WP_000736860.1 YhfG family protein -
  CR537_RS02445 (CR537_02450) fic 486059..486661 (+) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  CR537_RS02450 (CR537_02455) pabA 486693..487256 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  CR537_RS02455 (CR537_02460) argD 487342..488562 (+) 1221 WP_000963795.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CR537_RS02460 (CR537_02465) yhfK 488629..490719 (-) 2091 WP_001318073.1 YccS/YhfK family putative transporter -
  CR537_RS02465 (CR537_02470) crp 490770..491402 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CR537_RS02475 (CR537_02480) yhfA 491704..492108 (+) 405 WP_001148908.1 OsmC family protein -
  CR537_RS02480 (CR537_02485) prkB 492163..493032 (-) 870 WP_086525186.1 phosphoribulokinase -
  CR537_RS02485 (CR537_02490) yheU 493086..493304 (-) 219 WP_000907085.1 YheU family protein -
  CR537_RS02490 (CR537_02495) yheT 493298..494320 (-) 1023 WP_000057375.1 hydrolase -
  CR537_RS02495 (CR537_02500) yheS 494320..496233 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=210952 CR537_RS02465 WP_000242755.1 490770..491402(-) (crp) [Escherichia coli strain 14EC020]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=210952 CR537_RS02465 WP_000242755.1 490770..491402(-) (crp) [Escherichia coli strain 14EC020]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467