Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BUM85_RS03205 Genome accession   NZ_CP018842
Coordinates   623113..623742 (+) Length   209 a.a.
NCBI ID   WP_002475855.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain 14.1.R1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 618113..628742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUM85_RS03175 (BUM85_03140) isaB 618217..618753 (+) 537 WP_002447446.1 immunodominant staphylococcal antigen IsaB family protein -
  BUM85_RS03180 (BUM85_03145) - 618905..619891 (-) 987 WP_002447445.1 FUSC family protein -
  BUM85_RS03185 (BUM85_03150) map 620065..620820 (+) 756 WP_002447444.1 type I methionyl aminopeptidase -
  BUM85_RS03190 (BUM85_03155) - 620978..621364 (+) 387 WP_002475851.1 hypothetical protein -
  BUM85_RS03195 (BUM85_03160) liaF 621379..622080 (+) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  BUM85_RS03200 (BUM85_03165) vraS 622077..623123 (+) 1047 WP_002447441.1 sensor histidine kinase Regulator
  BUM85_RS03205 (BUM85_03170) vraR 623113..623742 (+) 630 WP_002475855.1 two-component system response regulator VraR Regulator
  BUM85_RS03210 (BUM85_03175) - 623799..624977 (-) 1179 WP_002447439.1 YihY/virulence factor BrkB family protein -
  BUM85_RS03215 (BUM85_03180) - 625383..625667 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  BUM85_RS03220 (BUM85_03185) - 625675..626139 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  BUM85_RS03225 (BUM85_03190) - 626281..626496 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  BUM85_RS03230 (BUM85_03195) - 626498..627739 (+) 1242 WP_002458545.1 aminopeptidase -
  BUM85_RS03235 (BUM85_03200) - 627820..628350 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23540.18 Da        Isoelectric Point: 4.7964

>NTDB_id=210923 BUM85_RS03205 WP_002475855.1 623113..623742(+) (vraR) [Staphylococcus epidermidis strain 14.1.R1]
MAIKILFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTGREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=210923 BUM85_RS03205 WP_002475855.1 623113..623742(+) (vraR) [Staphylococcus epidermidis strain 14.1.R1]
GTGGCGATTAAAATTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAAGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGGAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.258

100

0.943
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment