Detailed information NTG0210922

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BUM85_RS03200
• Genome accession: NZ_CP018842
• Coordinates: 622077..623123 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain 14.1.R1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 617077..628123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM85_RS03175 (BUM85_03140)	isaB	618217..618753 (+)	537	WP_002447446.1	immunodominant staphylococcal antigen IsaB family protein	-
BUM85_RS03180 (BUM85_03145)	-	618905..619891 (-)	987	WP_002447445.1	FUSC family protein	-
BUM85_RS03185 (BUM85_03150)	map	620065..620820 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
BUM85_RS03190 (BUM85_03155)	-	620978..621364 (+)	387	WP_002475851.1	hypothetical protein	-
BUM85_RS03195 (BUM85_03160)	liaF	621379..622080 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
BUM85_RS03200 (BUM85_03165)	vraS	622077..623123 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
BUM85_RS03205 (BUM85_03170)	vraR	623113..623742 (+)	630	WP_002475855.1	two-component system response regulator VraR	Regulator
BUM85_RS03210 (BUM85_03175)	-	623799..624977 (-)	1179	WP_002447439.1	YihY/virulence factor BrkB family protein	-
BUM85_RS03215 (BUM85_03180)	-	625383..625667 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
BUM85_RS03220 (BUM85_03185)	-	625675..626139 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
BUM85_RS03225 (BUM85_03190)	-	626281..626496 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
BUM85_RS03230 (BUM85_03195)	-	626498..627739 (+)	1242	WP_002458545.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=210922 BUM85_RS03200 WP_002447441.1 622077..623123(+) (vraS) [Staphylococcus epidermidis strain 14.1.R1]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=210922 BUM85_RS03200 WP_002447441.1 622077..623123(+) (vraS) [Staphylococcus epidermidis strain 14.1.R1]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTGGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACAAGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914