Detailed information NTG0210839

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: BUM80_RS07410
• Genome accession: NZ_CP018838
• Coordinates: 1359984..1360994 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 11A
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1354984..1365994

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM80_RS07385 (BUM80_07580)	-	1356239..1356533 (-)	295	Protein_1374	hypothetical protein	-
BUM80_RS07390 (BUM80_07585)	-	1356695..1357147 (+)	453	WP_000079148.1	universal stress protein	-
BUM80_RS07395 (BUM80_07590)	-	1357182..1358570 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
BUM80_RS07400 (BUM80_07595)	-	1358636..1359598 (+)	963	WP_001124786.1	asparaginase	-
BUM80_RS07405 (BUM80_07600)	-	1359627..1359920 (-)	294	WP_050375981.1	hypothetical protein	-
BUM80_RS07410 (BUM80_07605)	ccpA	1359984..1360994 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
BUM80_RS07415 (BUM80_07610)	-	1361419..1362018 (-)	600	WP_000866703.1	response regulator transcription factor	-
BUM80_RS07420 (BUM80_07615)	-	1362019..1363116 (-)	1098	WP_000893503.1	sensor histidine kinase	-
BUM80_RS07425 (BUM80_07620)	-	1363116..1363853 (-)	738	WP_000832916.1	ABC transporter permease	-
BUM80_RS07430 (BUM80_07625)	-	1363855..1364739 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
BUM80_RS07435 (BUM80_07630)	-	1364726..1364920 (-)	195	WP_000715302.1	hypothetical protein	-
BUM80_RS07440	-	1364917..1365123 (-)	207	Protein_1385	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=210839 BUM80_RS07410 WP_000990607.1 1359984..1360994(-) (ccpA) [Streptococcus pneumoniae strain 11A]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=210839 BUM80_RS07410 WP_000990607.1 1359984..1360994(-) (ccpA) [Streptococcus pneumoniae strain 11A]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568